Results 41 to 50 of about 2,755,876 (359)

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics

open access: yesThe ISME Journal, 2018
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Amanda N. Shelton   +6 more
semanticscholar   +1 more source

Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution

open access: yesNature Communications, 2021
Early vertebrate genomes were shaped by multiple whole-genome duplication (WGD) events of debated timings. Here the authors’ reconstruction of ancestral genomes using the probabilistic macrosynteny model supports a WGD shared by all vertebrates and a ...
Yoichiro Nakatani   +6 more
doaj   +1 more source

The Evolution of Comparative Phylogeography: Putting the Geography (and More) into Comparative Population Genomics

open access: yesGenome Biology and Evolution, 2021
Comparative population genomics is an ascendant field using genomic comparisons between species to draw inferences about forces regulating genetic variation.
S. Edwards   +3 more
semanticscholar   +1 more source

Evolution and comparative genomics of the most common Trichoderma species

open access: yesBMC Genomics, 2019
The growing importance of the ubiquitous fungal genus Trichoderma (Hypocreales, Ascomycota) requires understanding of its biology and evolution. Many Trichoderma species are used as biofertilizers and biofungicides and T. reesei is the model organism for
C. Kubicek   +16 more
semanticscholar   +1 more source

The evolution of comparative genomics [PDF]

open access: yesMolecular Genetics & Genomic Medicine, 2014
In this commentary I have only highlighted a few dimensions that comparative genomics has reached into. Looking at a PubMed search of publications with the exact combination and order of the words “comparative genomics” in the title or abstract identifies 3752 articles as of the date of this writing.
openaire   +3 more sources

Comparative genomic hybridization

open access: yesAnnual Review of Genomics and Human Genetics, 2005
▪ Abstract  Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14 , 35 , 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states.
Daniel, Pinkel, Donna G, Albertson
openaire   +2 more sources

Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data

open access: yesmBio
Whole-genome shotgun (WGS) metagenomic sequencing of microbial communities enables the discovery of the functions, physiologies, and evolutionary histories of prokaryotic and eukaryotic microbes.
Dandan Zhao   +5 more
doaj   +1 more source

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

open access: yesMolecules, 2016
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-modified antisense oligonucleotide (AO) sequences to induce exon 23 skipping in mdx mouse myotubes in vitro towards extending the ...
Suxiang Chen   +5 more
doaj   +1 more source

Comparative genomics of the major parasitic worms

open access: yesNature Genetics, 2017
Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating chronic infections of humans and animals, decimate crop production and are a major impediment to socioeconomic development.
International Helminth Genomes Consortium
semanticscholar   +1 more source

Exogenous Melatonin Attenuates Post-Harvest Decay by Increasing Antioxidant Activity in Wax Apple (Syzygium samarangense)

open access: yesFrontiers in Plant Science, 2020
Wax apple is one of the most popular tropical fruit but undergoes serious post-harvest decay during storage, transportation and marketing. Melatonin (MT) plays important roles in plant growth, development and stress responses.
Yao Chen   +10 more
doaj   +1 more source

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