Results 41 to 50 of about 427,581 (278)

Extreme mitochondrial reduction in a novel group of free-living metamonads

Nature Communications
Metamonads are a diverse group of heterotrophic microbial eukaryotes adapted to living in hypoxic environments. All metamonads but one harbour metabolically altered ‘mitochondrion-related organelles’ (MROs) with reduced functions, however the degree of ...
Shelby K. Williams, Jon Jerlström Hultqvist, Yana Eglit, Dayana E. Salas-Leiva, Bruce Curtis, Russell J. S. Orr, Courtney W. Stairs, Tuğba N. Atalay, Naomi MacMillan, Alastair G. B. Simpson, Andrew J. Roger   +10 more
doaj   +1 more source

Lipid Metabolism and Comparative Genomics [PDF]

, 2006
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette, Melrose, John, O’Malley, Brendan, Pickersgill, Laura, Rougier, Jonathan, Tindall, Marcus   +5 more
core  

Comparative Genomics of Cryptosporidium [PDF]

, 2013
Until recently, the apicomplexan parasites, Cryptosporidium hominis andC. parvum, were considered the same species. However, the two parasites, now considered distinct species, exhibit significant differences in host range, infectivity, and pathogenicity,
Alves, João M., Buck, Gregory A., Mazurie, Aurélien J., Ozaki, Luiz S., Schwartz, David C., Zhou, Shiguo   +5 more
core   +3 more sources

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Complete mitochondrial genome of Mahachai betta, Betta mahachaiensis (Teleostei: Osphronemidae)

Mitochondrial DNA. Part B. Resources, 2020
Mahachai bettas (Betta mahachaiensis) are distributed in areas of brackish water with Nipa Palms in Samut Sakhon, Thailand but urbanization is restricting their biodiversity. A complete mitochondrial genome (mitogenome) of B. mahachaiensis was determined
Worapong Singchat, Syed Farhan Ahmad, Nararat Laopichienpong, Aorarat Suntronpong, Tavun Pongsanarm, Thitipong Panthum, Nattakan Ariyaraphong, Navapong Subpayakom, Sahabhop Dokkaew, Narongrit Muangmai, Prateep Duengkae, Kornsorn Srikulnath   +11 more
doaj   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez, Jill O. Robinson, Wendy A. Allen‐Rhoades, Hadley S. Smith, Isabel Canfield, Rebecca L. Hsu, Sarah R. Scollon, Lauren R. Desrosiers‐Battu, Nicole M. Schneider, Frank Y. Lin, Donald Williams Parsons, Sharon E. Plon, Mary A. Majumder, Janet Malek, Amy L. McGuire   +14 more
wiley   +1 more source

Community Interaction Co-limitation: Nutrient Limitation in a Marine Microbial Community Context

Frontiers in Microbiology, 2022
The simultaneous limitation of productivity by two or more nutrients, commonly referred to as nutrient co-limitation, affects microbial communities throughout the marine environment and is of profound importance because of its impacts on various ...
Catherine Bannon, Insa Rapp, Insa Rapp, Erin M. Bertrand   +3 more
doaj   +1 more source

GMOD for Evolutionary Biology [PDF]

, 2010
The Generic Model Organism Database (GMOD, "http://gmod.org":http://gmod.org) project provides interoperable, open source software tools for managing, visualizing and annotating biological data.
Dave Clements, Robert Buels
core   +1 more source

Approximating Weighted Duo-Preservation in Comparative Genomics

, 2017
Motivated by comparative genomics, Chen et al. [9] introduced the Maximum Duo-preservation String Mapping (MDSM) problem in which we are given two strings $s_1$ and $s_2$ from the same alphabet and the goal is to find a mapping $\pi$ between them so as ...
AR Mushegian, B Brubach, G Cormode, H Jiang, KM Swenson, L Bulteau, M Chrobak, N Boria, NH Mustafa, RC Hardison, S Beretta, TM Chan, W Chen, X Chen   +13 more
core   +1 more source

Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]

, 2018
Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J., Hedlund, Brian P., Hua, Zheng-Shuang, Knight, Rob, Li, Wen-Jun, Li, Yu-Xian, Liu, Lan, Qi, Yan-Ling, Qu, Yan-Ni, Rao, Yang-Zhi, Shu, Wen-Sheng, Tian, Ye, Yin, Yi-Rui, Zhou, En-Min, Zhu, Qiyun   +14 more
core   +3 more sources