Results 61 to 70 of about 427,581 (278)

Identification and expression analysis of GRAS transcription factors in the wild relative of sweet potato Ipomoea trifida

BMC Genomics, 2019
Background GRAS gene is an important transcription factor gene family that plays a crucial role in plant growth, development, adaptation to adverse environmental condition.
Yao Chen, Panpan Zhu, Shaoyuan Wu, Yan Lu, Jian Sun, Qinghe Cao, Zongyun Li, Tao Xu   +7 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Comparative genomics of Cluster O mycobacteriophages [PDF]

, 2015
Mycobacteriophages - viruses of mycobacterial hosts - are genetically diverse but morphologically are all classified in the Caudovirales with double-stranded DNA and tails.
Adair, T, Anders, KR, Ball, S, Bollivar, D, Bowman, CA, Breitenberger, C, Burnett, SH, Butela, K, Byrnes, D, Carzo, S, Cornely, KA, Cresawn, SG, Cross, T, Daniels, RL, De Los Santos, C, Dedrick, RM, Dunbar, D, Ekanem, K, Findley, AM, Gissendanner, CR, Golebiewska, UP, Hartzog, GA, Hatfull, GF, Hatherill, JR, Hendrix, RW, Hughes, LE, Jacobs-Sera, D, Jalloh, CS, Khambule, SL, King, RA, King-Smith, C, Klyczek, K, Krukonis, GP, Laing, C, Lapin, JS, Lopez, AJ, Mkhwanazi, SM, Molloy, SD, Moran, D, Munsamy, V, Pacey, E, Plymale, R, Pope, WH, Poxleitner, M, Reyna, N, Russell, DA, Schildbach, JF, Stukey, J, Taylor, SE, Ware, VC, Wellmann, AL, Westholm, D, Wodarski, D, Zajko, M, Zikalala, TS   +54 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development

Cell Reports, 2017
There are nearly 400 modern domestic dog breeds with a unique histories and genetic profiles. To track the genetic signatures of breed development, we have assembled the most diverse dataset of dog breeds, reflecting their extensive phenotypic variation ...
Heidi G. Parker, Dayna L. Dreger, Maud Rimbault, Brian W. Davis, Alexandra B. Mullen, Gretchen Carpintero-Ramirez, Elaine A. Ostrander   +6 more
doaj   +1 more source

The Cyclic AMP Receptor Protein, Crp, Is Required for the Decolorization of Acid Yellow 36 in Shewanella putrefaciens CN32

Frontiers in Microbiology, 2020
Shewanella shows good application potentials in the decolorization and detoxification of azo dye wastewater. However, the molecular mechanism of decolorization is still lacking. In this study, it was found that Shewanella putrefaciens CN32 exhibited good
Weijie Liu, Ying Chen, Xuge Zhou, Jiawen Liu, Jingrong Zhu, Shiwei Wang, Cong Liu, Di Sun   +7 more
doaj   +1 more source

The URGI plants and bio-agressors genomics annotation system [PDF]

, 2009
The URGI genomic annotation platform, developed in the framework of the GnpAnnot project, relies on well known GMOD tools (http://gmod.org): Apollo, Chado and GBrowse.
Alaux, Michael, Amselem, Joelle, Brault, Baptiste, Legeai, Fabrice, Luyten, Isabelle, Quesneville, Hadi, Reboux, Sébastien, Sidibé-Bocs, Stéphanie, Steinbach Samson, Delphine   +8 more
core  

Gramene 2013: comparative plant genomics resources [PDF]

, 2014
Gramene (http://www.gramene.org) is a curated online resource for comparative functional genomics in crops and model plant species, currently hosting 27 fully and 10 partially sequenced reference genomes in its build number 38.
Amarasinghe, V., Bolser, D., Croft, D., D'Eustachio, P., Dharmawardhana, P., Haw, R., Jaiswal, P., Jiao, Y., Kerhornou, A., Kersey, P. J., Kumari, S., Lu, Z., Monaco, M. K., Naithani, S., Olson, A., Pasternak, S., Preece, J., Staines, D., Stein, J., Stein, L., Thomason, J., Walts, B., Ware, D., Wei, S., Wu, G., Youens-Clark, K.   +25 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source