Results 111 to 120 of about 3,825,947 (299)

The Comparative Method in Biology and the Essentialist Trap

open access: yesFrontiers in Ecology and Evolution, 2018
The comparative method is at the center of a complex view of biology, according to which organisms are seen as historical products. This is a dynamic view of nature, where genotypes and phenotypes change over evolutionary time under the influence of ...
Pedro Martinez, Pedro Martinez
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Tendencias en educación y brecha regional. Indicadores del sistema educativo en Canarias (1990-2014)

open access: yesRevista Atlántida, 2020
En este artículo se tratará de mostrar, de forma descriptiva y comparativa, la evolución del sistema educativo canario (tomando como referencia desde los años 90 hasta la actualidad), con el objetivo de ofrecer una panorámica de la educación en Canarias ...
Josué Gutiérrez Barroso
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Comparative and Competitive Advantage of the Shrimp Industry in Mekong River Delta, Vietnam [PDF]

open access: yes
Given the growing prominence of Vietnam's fishery products in the world market, this study examines data on shrimp aquaculture in the country, as practiced through intensive and semi-intensive methods, in two provinces in the Mekong River Delta region ...
Nguyen Tuan Kiet, Zenaida M. Sumalde
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Molecular dynamics simulation of growth of Cu nanoclusters from Cu-ions in a plasma

open access: yes, 2014
A recently developed method of nanoclusters growth in a pulsed plasma is studied by means of molecular dynamics. A model that allows one to consider high-energy charged particles in classical molecular dynamics is suggested, and applied for studies of ...
Abrikosov, Igor A.   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The first phylogenetic reconstruction of Nippostrongylinae (Nematoda: Heligmonellidae) reveals 3 new genera, the polyphyletic nature of Carolinensis and Vexillata, and identifies 5 clades with varying associations with mammals

open access: yesParasitology
The Nippostrongylinae is a group of strongylid nematodes that includes species typically associated with coprophagous mammals; in the New World, it is represented by 82 species within 11 genera.
F. Agustín Jiménez   +10 more
doaj   +1 more source

Reflective Outcomes in Asynchronous Computer Mediated Communication: A Case Study using a Comparative Method [PDF]

open access: yes, 2011
In an era of constant educational reforms, many acknowledge teachers’ professional development as the keystone to educational improvement. The issue of whether teachers’ development is adequate has been crucial in all times, especially now that ...
PAVLIDOU, AIKATERINI
core  

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