Results 141 to 150 of about 3,825,947 (299)

Microbiomes, Community Ecology, and the Comparative Method. [PDF]

mSystems, 2019
Hird SM.
europepmc   +1 more source

An efficient frequency response solution for nonproportionally damped systems [PDF]

A method is presented to accurately and economically calculate steady state frequency responses based on the analysis of large finite element models with nonproportional damping effects.
Conti, Paul, Rule, William K.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Interpreting Developed Countries' Foreign Direct Investment [PDF]

Inward and outward direct investment (FDI) stocks and flows tend to go together, across countries and over time. The countries that invest extensively abroad are usually also large recipients of FDI. There is little evidence that flows of FDI are a major
Robert E. Lipsey
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Down selecting adjuvanted vaccine formulations: a comparative method for harmonized evaluation. [PDF]

BMC Immunol, 2018
Younis SY, Barnier-Quer C, Heuking S, Sommandas V, Brunner L, Vd Werff N, Dubois P, Friede M, Kocken C, Collin N, Remarque E.   +10 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

M. Sokolová, M. Vojteková, W. Mirosławska, M. Kyseľová, Slovenčina a poľština. Synchrónne porovnanie s cvičeniami. Prešov: Prešovská univerzita v Prešove, 2012; 322 ss.

Studia z Filologii Polskiej i Słowiańskiej, 2014
Halina Mieczkowska
doaj   +1 more source

The Independent Evolution Method Is Not a Viable Phylogenetic Comparative Method. [PDF]

PLoS One, 2015
Griffin RH, Yapuncich GS.
europepmc   +1 more source