Results 91 to 100 of about 1,261,912 (332)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A humanistic approach to organizations and to organizational decision-making [PDF]

open access: yes
This paper attempts to take steps towards the formulation of a more human approach to the theory of the firm than the conventional economics-based models.
Rosanas, Josep M.
core  

Can the competence-based approach contribute to Inclusion and Citizenship? [PDF]

open access: yes, 2011
En este trabajo intentamos contestar a la pregunta acerca de la medida en que el enfoque de las competencias puede contribuir a la formación de ciudadanos y a la inclusión educativa del alumnado. Para ello, abordaremos tres grandes temas. En primer lugar,
Martín Ortega, Elena   +1 more
core   +3 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

SPECIFICS OF ELABORATING METHODOLOGY TO TEACH INNOVATIVE COMPETENCE USING EMBEDDABLE MODULE

open access: yesИнтеграция образования, 2016
Introduction: the article is concerned with the development of competence when teaching students innovative activity. The analysis of bachelor’s degree programmes in engineering and technology demonstrates the absence of competencies for innovation ...
Nikolai I. Naumkin   +4 more
doaj   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou   +12 more
wiley   +1 more source

Fostering communicative competence: A task-based approach to public speaking materials development

open access: yesJournal of Applied Linguistics and Literature
While ample studies have explored the creation of task-based materials to enhance the English proficiency of university students, there has been limited research on how such materials can be tailored to promote university students' public speaking ...
Ariatna Ariatna
doaj   +1 more source

Gamification in the competence-based approach

open access: yesKANT, 2021
The rapid and widespread introduction of education based on competencies is the creation of a competent approach to learning, where the main goal is to train specialists who can skillfully respond to a rapidly changing world. The competence-based approach forces us to change the usual pedagogical beliefs that occur in the educational process: methods ...
openaire   +1 more source

Situating Grammar Instruction in the World Language Classroom: Four Content-Enriched Strategies [PDF]

open access: yes, 2009
The role of grammar instruction in promoting communicative competence continues to be a controversial issue for the world language classroom teacher. Second language acquisition research suggests that critical to sustained progress in language use is a ...
Hernández, Todd A.
core   +1 more source

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