Results 71 to 80 of about 1,222,459 (387)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

COMPETENCE AND PERFORMANCE IN THE TEACHING PROFESSION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
An educational institution is a place blessed within its mission full of nobility and generosity-that of forming and cultivating personalities, shaping livings, of creating individualities, opening gates to culture, prompting the knowledge, and building
GEORGETA ANDRONACHE (GOGEANU)
doaj  

Kinerja Pegawai Ditinjau Dari Kompetensi, Kompensasi, Motivasi Kerja, dan Disiplin Kerja

open access: yesJurnal Manajemen Stratejik dan Simulasi Bisnis, 2023
The success of the hospital in providing the best and quality service to the community can be measured by the quality of the performance of its human resources.
Yenni Rosyinah Hasibuan   +2 more
doaj   +1 more source

Pengaruh Pelatihan, Pengalaman dan Kompetensi Kerja terhadap Kinerja pada PT. Permodalan Siak [PDF]

open access: yes, 2015
The quality of human resources is determined by the extent to which the system in the field of human resources able to support and satisfy the desires of the employees and the company.
Amsal, C. (Chairul)   +2 more
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

The Readiness of Educational Competency in Higher Education in Connecting the Era of Industrial Revolution 4.0 [PDF]

open access: yesSHS Web of Conferences, 2020
Universities within the era of the 4.0 industrial revolution, now must immediately improve in preparing themselves, especially related to human resources.
Br Sitepu Rismawati   +3 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Ageism in Rheumatology: The Health Care Professional's Perspective

open access: yesArthritis Care &Research, EarlyView.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith   +4 more
wiley   +1 more source

Pengaruh Kepemimpinan Dan Kompetensi SDM Terhadap Kinerja Pegawai Inspektorat Jenderal Kementerian Pendidikan Dan Kebudayaan Jakarta [PDF]

open access: yes, 2016
This research entitled “Analysis of The Effect of Leadership and Competence of Human Resources on Employees Job Performance in Inspektorat Jenderal Kementerian Pendidikan dan Kebudayaan”.
Lestari, H. (Hesti)   +2 more
core  

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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