Results 61 to 70 of about 427,425 (296)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Creativity in contemporary higher education in the context of the artificial intelligence expansion
Creativity StudiesIn the paper it is discussed what are the potential possibilities to foster creativity in contemporary higher education in the context of the artificial intelligence expansion based on theoretical analysis of sources and the findings of a pilot empiric ...
Edita Butrimė, Vaiva Zuzevičiūtė
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
L’évaluation des élèves en France, à un moment charnière de leur histoire?
Mesure et Évaluation en Éducation, 2009 L’éducation nationale française est fortement centralisée : programmes, horaires et sujets d’examen nationaux, autonomie des établissements quasi nulle jusqu’à aujourd’hui.
Anne-Marie Bardi, Marie Mégard
doaj +1 more source
Библиосфера, 2019 The article deals with the attitude of specialists to the competence approach in higher education, the stages of the “competence” formation concept are shown.
J. Zemengue, T. Mbila
doaj +1 more source
Key Competences in Europe: Opening Doors For Lifelong Learners Across the School Curriculum and Teacher Education [PDF]
The aim of the study is to provide a comparative overview of policy and practice concerning the development and implementation of key competences in the education systems of the 27 Member States of the European Union.
Alain Michel +7 more
core
Competencies of Polish Scientists as a Contribution to the Success of Innovation Research and Development Projects [PDF]
, 2013 The states which top the list of the number of conducted research and development activities put substantial emphasis on a scientist’s competencies. Today, experts are able to determine the competencies that will decide on the success of projects in ...
Knapińska, Anna, Tomczyńska, Aldona
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Endogenous competences and linkages development [PDF]
In this paper we analyze empirically the influence of firms’ endogenous competences in the existence, quality and results of the linkages between firms and different types of agents.
Erbes, Analía +2 more
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source