Results 101 to 110 of about 510,436 (298)

Desarrollo de competencias: enfoque para la gestión de la biblioteca universitaria [PDF]

open access: yes, 2010
The article presents a model for information literacy in university libraries developed on competencies profiles and competency-based approach of the degrees offered at the University of ...
Quevedo-Pacheco, Nelva
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

COMPARATIVE ANALYSIS BETWEEN NURSING CORE COMPETENCY STANDARDS OF AUSTRALIA AND THE PHILIPPINES

open access: yesBelitung Nursing Journal, 2019
Philippines as one of the top producers of nurses worldwide must benchmark its national nursing standards to the rest of the world. Therefore, the standards must be compared and contrasted with other countries like Australia.
Rainier C. Moreno-Lacalle
doaj   +1 more source

Компентентнісний підхід до професійної підготовки майбутніх фахівців інженерно-технічного профілю [PDF]

open access: yes, 2012
The article is devoted to the training of future professionals of engineering profile, which is based on the competence approach. Analyzes the concept of competence approach different authors.
Друзь, Ірина Миколаївна
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Outcomes are what matter: Competency-based medical education gets us to our goal

open access: yesMedEdPublish, 2018
Health professions education is undergoing a major paradigm shift to competency-based medical education. When shifts in thinking are profound and result in transformations of existing paradigms, there is often an accompanying criticism.
Shelley Ross   +2 more
doaj  

Multi competence and professional teaching [PDF]

open access: yesRevista Electrónica Interuniversitaria de Formación del Profesorado, 2011
This article shows a brief theoretical description of current competency-based approaches and some definitions of the concept competency as it has been used in initial teacher training processes, and another aims at providing new highlights and a ...
Alex Pavíe
doaj  

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