Results 71 to 80 of about 5,888,200 (304)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Building a Team of Teachers for Designing and Implementation of Modul Educational Programs

Психологическая наука и образование (2007. Online), 2015
This article can be classified as thematic review, since it shows the actual experience of a human resources choice for the design and implementation of modular educational programs.
Kashtanova S.N. , Kudryavtsev V.A.
doaj   +1 more source

The competency-based approach to training

Medical Journal of Indonesia, 1996
This paper describes the competency-based training (CBT) approach that was presented at a pre-congress seminar entitled "Learning Without Walls" that was held on October 13-14 1995 in Bali Indonesia in conjunction with the XVth Asian and Oceanic Congress of Obstetrics and Gynecology. A small group of decision makers was given the opportunity to update
Rick Sullivan, Noel McIntosh
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Validating Competency Based Approach to Human Resource Training [PDF]

مطالعات مدیریت بهبود و تحول, 2013
The use of Competency based human resource management systems are increasingly growth. In this paper, the concepts of training, human resource development and competency are reviewed, then focused and examine the design and implementation of competency ...
Mani Arman, Mahboubeh Khosravi
doaj  

Mixing rich and asynchronous communication for new service development performance [PDF]

, 2015
This article explores the nature of relationships between internal communication modes, new service development (NSD) competencies (specifically learning and development competencies) and NSD performance.
Akgün, Akgün, Alam, Alam, Anbari, Antioco, Armstrong, Atuahene-Gima, Avlonitis, Bello, Blazevic, Bracken, Brentani, Burke, Busby, Cadwallader, Chin, Chin, Cohen, Cooper, Daft, Danneels, De Luca, Dennis, Dennis, Ettlie, Fornell, Fornell, Froehle, Gibson, Goffin, Gopesh, Hair, Hansen, Hargadon, Harmancioglu, Henard, Henseler, Hertog, Hsia, Hull, Johne, Kahn, Keller, Kerr, Kim, Kivimäki, Kleinschmidt, Koners, Kowalkowski, Lei, Lievens, Lilly, Madhavan, Maltz, Marsh, Marsh, Massey, Maznevski, McKee, McKee, Menor, Menor, Meyers, Miles, Millson, Moenaert, Montoya, Montoya-Weiss, Montoya-Weiss, Moorman, Narver, Newell, Nonaka, Ordanini, Pazos, Pinto, Podsakoff, Robert, Robert, Salo, Schreyögg, Song, Song, Song, Song, Sproull, Storey, Storey, Storey, Storey, Subramaniam, Szulanski, Tenenhaus, Thatcher, Venkatraman, Voss, Walsh, Wang, Watson-Manheim, Wetzels, Zedtwitz, Zippel-Schultz, Zollo   +103 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

COMPETENCY-BASED APPROACH AND TOOLS FOR STUDENT TRAINING QUALITY EVALUATION IN ADAPTIVE E-LEARNING COURSES

Sovremennye Issledovaniâ Socialʹnyh Problem, 2018
Purpose. The necessity of developing new approaches to evaluating the quality of training outcomes arises in the context of developing trends for competency-based approach and person-centered virtual electronic environment.
Yulia Vladimirovna Vainshtein, Viktoriya Anatol’evna Shershneva, Vitalii Isaakovich Vainshtein, Irina Fedorovna Kosmidis   +3 more
doaj   +1 more source

COMPETENCE-BASED APPROACH TO LSP-TRANSLATION

Philology at MGIMO, 2020
The article presents the model of professional translator competences related to three levels of the ‘second language personality’. The article describes the development of translator competences (communicative, extra-linguistic and specialized ones) on the basis of the well-formed competence in the basic branch of study (the student’s major).
M. Ye. Korovkina, A. L. Semenov, V. I. Ershov   +2 more
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source