Results 51 to 60 of about 2,915,090 (307)

Cultural Competency in Dramatherapy Training [PDF]

open access: yes, 2022
This research grew out of the researcher’s experience encountered during their Dramatherapy training. It explores the concept of cultural competency and ways in which it can be embedded in the training.
Sunday, L.
core   +1 more source

Competence-based approach in the training of physicists

open access: yesJournal of Physics: Conference Series, 2021
Abstract Competence is the ability of an individual to solve various practical tasks, a set of knowledge, skills and abilities required to perform a specific practical activity. The use of intersubject connections during the training of physicists, in our opinion, will make it possible to prepare specialists with a broad Outlook and good
Vasylyshyn, Vitalii   +8 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Using a Competency Approach to Understand HCN Managers in Asia: A Study of Japanese, Chinese, Malaysian, Thai, and Hong Kong Managers in Japanese MNEs [PDF]

open access: yes, 2010
This study examined host country nationals (HCNs) in multinational enterprises (MNEs) through the lens of a competency approach. Participants consisted of 500 managers working for a leading Japanese retail MNE, with 100 each from Japan, China, Malaysia ...
山崎, 佳孝   +4 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Contemplation on Competency-based Curriculum in Medical Education [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2016
Introduction: One of the approaches to explaining the relationship between education and the world of work, and reducing the gap between students’ knowledge and their professional needs is competency-based curriculum.
Akbar Hedayati   +3 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Developing a Personal Leadership Competency Model for Safety Managers: A Systems Thinking Approach

open access: yes, 2022
The roles of all levels of management in influencing safety, particularly in a complex work environment, are crucial. Therefore, safety managers need to develop leadership competencies (i.e., effectiveness in terms of person-oriented behaviours) to ...
Alidrisi, Hassan M.   +4 more
core   +1 more source

L’internationalisation de l’approche par compétences, le cas du Mexique, entre transfert de modèle et résistance

open access: yesCahiers de la Recherche sur l'Education et les Savoirs, 2017
At the global level the competency based approach (CBA) is today the pedagogical approach which underlies most educational reforms. Originating in the professional and vocational world, this approach found defenders in the academic world as well as among
Nathalie Portilla
doaj   +1 more source

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