Results 61 to 70 of about 2,915,090 (307)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Professionally Oriented Practice in Graduate Students in the Context of Networking between University and School

Психологическая наука и образование (2007. Online), 2016
The paper describes the experience of organising professionally oriented practice for graduate students in the context of networking. The model of in-depth professionally oriented practice for students of the master’s programme in Psychology and ...
Gutina G.Y., , Yemelyanova I.V.,
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Building a Team of Teachers for Designing and Implementation of Modul Educational Programs

Психологическая наука и образование (2007. Online), 2015
This article can be classified as thematic review, since it shows the actual experience of a human resources choice for the design and implementation of modular educational programs.
Kashtanova S.N. , Kudryavtsev V.A.
doaj   +1 more source

Operationalization of Competency-Based Approach: From Competency-Based Education to Integration Pedagogy

, 2017
Advocates of integration pedagogy such as Peyser et al. (2006) and Roegiers (2010) consider this instructional approach as a distinct pedagogical trend, while opponents of this view such as Hirtt (2009) regard integration pedagogy and competency-based education (CBE) as two sides of the same coin.
Arab World English Journal, Slimane BOUKHENTACHE   +1 more
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The competency-based approach as methodology of professional training of future teachers in the conditions of education informatization

, 2020
Kharkivska A.A. The competency-based approach as methodology of professional training of future teachers in the conditions of education informatization / A.A. Kharkivska // Проблеми інженерно-педагогічної освіти : зб. наук. пр. / Укр. інж.-пед. акад. – Х.
Kharkivska, Alla
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

COMPETENCY-BASED APPROACH AND TOOLS FOR STUDENT TRAINING QUALITY EVALUATION IN ADAPTIVE E-LEARNING COURSES

Sovremennye Issledovaniâ Socialʹnyh Problem, 2018
Purpose. The necessity of developing new approaches to evaluating the quality of training outcomes arises in the context of developing trends for competency-based approach and person-centered virtual electronic environment.
Yulia Vladimirovna Vainshtein, Viktoriya Anatol’evna Shershneva, Vitalii Isaakovich Vainshtein, Irina Fedorovna Kosmidis   +3 more
doaj   +1 more source

TEACHING WITHIN THE COMPETENCY- BASED APPROACH

RIMAK International Journal of Humanities and Social Sciences, 2021
The Education Sector is Considered One of The Most Important Issues That Have Occupied The Minde Of Many Schoalrs And Researchers, given its Importance At The Global And National Level, As It Is An Essential And Effective Element in building and developing Countries And Advancing Societies.
Samir NOUIRI, Sabrina RAMASH
openaire   +1 more source