Results 31 to 40 of about 28,432,988 (289)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Exploring competency-based medical education among specialist doctors in Malaysia [PDF]

, 2017
This research was done with the objective to explain the development process of medical specialist when they went through continuous learning process via the Continuing Professional Education (CPE) upon being recognized as a medical specialist.
Tukiman, Nur Fariza, Zainal Abiddin, Norhasni   +1 more
core   +1 more source

The Need for Competency-Based Education

American Journal of Pharmaceutical Education
While pharmacy education updates learning as new information arises, changes to learning experiences can trail behind current practices and technology. There have been multiple calls for radical changes in how health professions education is delivered to ensure patients are receiving high-quality care.
Denise H, Rhoney, Aleda M H, Chen, Mariann D, Churchwell, Kimberly K, Daugherty, Jennie B, Jarrett, Erika L, Kleppinger, James J, Nawarskas, Stephanie L, Sibicky, Cindy D, Stowe, Susan M, Meyer   +9 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

DESIGNING COMPETENCY BASED HIGHER EDUCATION CURRICULUM: STRATEGIES AND ACTIONS [PDF]

, 2023
Emerging educational trends globally and the changing needs of society and learners dictate the need for regular curriculum reviews and development in higher education.
Syomwene, Anne
core   +1 more source

Competency-based medical education for Indian undergraduates: Where do we stand?

APIK Journal of Internal Medicine
The traditional system of medical education was a structure and process-based system with limited assessment of application of knowledge, skills, and attitudes.
Mamta Gehlawat, Goutham Thumati, Priyanka Samala, Chaganti Lalitha Alekhya, Are Shailaja, Anamika Sharma   +5 more
doaj   +1 more source

Contemplation on Competency-based Curriculum in Medical Education [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2016
Introduction: One of the approaches to explaining the relationship between education and the world of work, and reducing the gap between students’ knowledge and their professional needs is competency-based curriculum.
Akbar Hedayati, Hasan Maleki, Ali reza Sadeghi, Esmaeil Saadipour   +3 more
doaj  

Exploring Latent Topics and International Research Trends in Competency-Based Education Using Topic Modeling

Education Sciences, 2021
Recently, there has been growing educational interest in competency. Global organizations, such as the United Nations (UN) and Organization for Economic Co-operation and Development (OECD), which are leading the discourse on education reform, are ...
Seungsu Paek, Taehun Um, Namhyoung Kim
doaj   +1 more source