Results 51 to 60 of about 1,233,660 (307)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Exploring competency-based medical education among specialist doctors in Malaysia [PDF]

open access: yes, 2017
This research was done with the objective to explain the development process of medical specialist when they went through continuous learning process via the Continuing Professional Education (CPE) upon being recognized as a medical specialist.
Tukiman, Nur Fariza   +1 more
core  

Current Trend of Accreditation within Medical Education [PDF]

open access: yes, 2020
Currently, accreditation within medical education is a priority on the agenda for many countries worldwide. The World Federation for Medical Education’s (WFME) launch of its first trilogy of standards in 2003 was a seminal event in promoting ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A Competence-based System for Recommending Study Materials from the Web (CBSR) [PDF]

open access: yes, 2010
A pedagogically-informed approach to the design of an e-learning system is important since an effective learning system requires teaching activities that match the students’ learning requirements.
Lester Gilbert   +5 more
core   +1 more source

COMPETENCY-BASED EDUCATION: THEORY AND PRACTICE

open access: yesPsycho-Educational Research Reviews, 2021
This study aimed to reach a pro on Competency-Based Education (CBE) through the opinions of Educational Sciences experts and to review the literature on CBE. In this study, convergent design, one of the mixed methods research, was used, and a semi-structured questionnaire was used to collect data.
Açıkgöz, Tacettin   +1 more
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Milestones and Competency-Based Medical Education [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī
Dear Editor Competency-Based Medical Education (CBME) in medical education is defined as “an outcomes-based approach to the design, implementation, assessment, and evaluation of medical education programs using a competency-based organizational ...
Hamid Mahdavifard
doaj  

Impact of faculty development in curriculum implementation support program (CISP II) training on execution of competency-based medical education

open access: yesKanem Journal of Medical Sciences, 2023
Background: Medical education in our country has so far been commendable and comparable with international standards in terms of educating a competent medical practitioner.
Suma S   +4 more
doaj   +1 more source

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