Results 61 to 70 of about 17,117 (263)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Competences and Competence Model of University Teachers

Procedia - Social and Behavioral Sciences, 2014
AbstractCompetences represent a summary of key professional and personal skills/talents and behavioural patterns of an individual. They form the basis of any proficient working behaviour, and the level of their maturity is crucial for the successful performance of the profession concerned. From this point of view, the competences of university teachers
Blašková, Martina, Blaško, Rudolf, Kucharčíková, Alžbeta   +2 more
openaire   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Utilizing dematel method in competency modeling

Forum Scientiae Oeconomia, 2014
Competency models, which should be designed for all key positions in the company, show what competencies are necessary for individual position(s). The question is what the key competencies for each position are.
Katerina Kashi, Jiri Franek
doaj  

Research on the effect of professional competency of college physical education teachers on students’ motivation for physical education learning

Frontiers in Psychology
IntroductionThis study, based on self-determination theory, constructs a multilevel model to examine the impact of the professional competency of college physical education teachers (PCCPET) on students’ motivation for physical education learning (SMPEL).
Wanhong Luo, Xu Sun, Zongkai Zhou, Zuguo Tian, Zichao Chen   +4 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Socioeconomic status and educational inequality: digital competency pathways to creative problem-solving and academic performance

Frontiers in Psychology
IntroductionThe digital divide extends beyond technology access to create educational inequalities through differential competency development, where socioeconomic advantages enable sustained digital engagement that enhances creative problem-solving ...
Jinglu Liu, Yuwei Chen
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Employee Performance with Employee Engagement as an Intervening Variable: Individual Career Development and Competency

Jurnal Manajemen Universitas Bung Hatta
By using employee engagement as an intervening variable, this research aims to find out how individual career development and competency impact the performance of Bank Nagari Pangkalan employees.
Sitti Rizki Mulyani, Zikri Trinanda, Fitri Yeni, M. Afuan, Nurhamzah   +4 more
doaj   +1 more source