Results 51 to 60 of about 231,421 (295)
Reaching Agreement in Competitive Microbial Systems [PDF]
arXiv, 2021 We study distributed agreement in microbial distributed systems under stochastic population dynamics and competitive interactions. Motivated by recent applications in synthetic biology, we examine how the presence and absence of direct competition among microbial species influences their ability to reach majority consensus. In this problem, two species
arxiv
New Conditional Symmetries and Exact Solutions of the Diffusive Two-Component Lotka–Volterra System
Mathematics, 2021 The diffusive Lotka–Volterra system arising in an enormous number of mathematical models in biology, physics, ecology, chemistry and society is under study. New Q-conditional (nonclassical) symmetries are derived and applied to search for exact solutions
Roman Cherniha, Vasyl’ Davydovych
doaj +1 more source
Kin Selection in the RNA World
Life, 2017 Various steps in the RNA world required cooperation. Why did life’s first inhabitants, from polymerases to synthetases, cooperate? We develop kin selection models of the RNA world to answer these questions.
Samuel R. Levin, Stuart A. West
doaj +1 more source
LAG3’s Enigmatic Mechanism of Action
Frontiers in Immunology, 2021 LAG3 is an important immune checkpoint with relevance in cancer, infectious disease and autoimmunity. However, despite LAG3’s role in immune exhaustion and the great potential of LAG3 inhibition as treatment, much remains unknown about its biology ...
Colin G. Graydon +5 more
doaj +1 more source
Direct competition results from strong competiton for limited resource [PDF]
Journal of Mathematical Biology (2013) 0303-6812, 2012 We study a model of competition for resource through a chemostat-type model where species consume the common resource that is constantly supplied. We assume that the species and resources are characterized by a continuous trait. As already proved, this model, although more complicated than the usual Lotka-Volterra direct competition model, describes ...
arxiv +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Ethical framework on risk governance of synthetic biology
Journal of Biosafety and Biosecurity, 2023 Synthetic biology is an emerging multidisciplinary field that aims to design and construct new biological systems not found in nature. Whereas synthetic biology may yield tremendous benefits, it may also pose substantial risks to human health and the ...
Liao Bohua +5 more
doaj
Biosfer, 2021 Scientific reasoning and problem-solving have become primary interests in 21st-century education. These skills have an essential role in preparing students to face global competition.
Maisuna Kundariati +5 more
doaj +1 more source
Predicting coexistence of plants subject to a tolerance-competition trade-off [PDF]
, 2013 Ecological trade-offs between species are often invoked to explain species coexistence in ecological communities. However, few mathematical models have been proposed for which coexistence conditions can be characterized explicitly in terms of a trade-off. Here we present a model of a plant community which allows such a characterization.
arxiv +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source