Results 101 to 110 of about 1,441,098 (322)

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.

open access: yesBlood, 2019
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies including anti-beta-2-glycoprotein-I (anti-β2GPI) that are considered central to APS pathogenesis.
Shruti Chaturvedi   +12 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Lagrangian Embeddings and Holomorphic Discs in the Complement of Complex Hypersurfaces [PDF]

open access: yesarXiv, 1998
For a given embedded Lagrangian in the complement of a complex hypersurface we show existence of a holomorphic disc in the complement having boundary on that Lagrangian.
arxiv  

Production of complement components by cells of the immune system

open access: yesClinical and Experimental Immunology, 2017
The complement system is an important part of the innate immune defence. It contributes not only to local inflammation, removal and killing of pathogens, but it also assists in shaping of the adaptive immune response.
R. Lubbers   +3 more
semanticscholar   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

The human factor H protein family – an update

open access: yesFrontiers in Immunology
Complement is an ancient and complex network of the immune system and, as such, it plays vital physiological roles, but it is also involved in numerous pathological processes.
Noémi Sándor   +13 more
doaj   +1 more source

Geometric limits of knot complements, II: Graphs determined by their complements [PDF]

open access: yesarXiv, 2009
We prove that there are compact submanifolds of the 3-sphere whose interiors are not homeomorphic to any geometric limit of hyperbolic knot complements.
arxiv  

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