Results 91 to 100 of about 2,630,357 (343)

On the cohomology of discriminantal arrangements and Orlik-Solomon algebras

open access: yes, 1998
We relate the cohomology of the Orlik-Solomon algebra of a discriminantal arrangement to the local system cohomology of the complement. The Orlik-Solomon algebra of such an arrangement (viewed as a complex) is shown to be a linear approximation of a ...
Cohen, Daniel C.
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Functional Characterization of the Disease-Associated N-Terminal Complement Factor H Mutation W198R

open access: yesFrontiers in Immunology, 2017
Dysregulation of the complement alternative pathway is involved in the pathogenesis of several diseases, including the kidney diseases atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G).
Marcell Cserhalmi   +8 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Yunfeng Liu   +5 more
doaj   +1 more source

Effects of Climatic Conditions and Genotypes on Vitamin C Levels in Stone Species and Apple Cultivars

open access: yesPlants
Genetic and climatic factors influence the nutritional content of fruit, with vitamin C being a key component. Using HPLC, we quantified the amount of vitamin C in cherries, apricots, plums, and apples from 2022 to 2024.
Aneta Bílková   +4 more
doaj   +1 more source

Generic hyperbolic knot complements without hidden symmetries [PDF]

open access: green, 2019
Eric Chesebro   +2 more
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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