Results 71 to 80 of about 2,630,357 (343)
Nephritic Factors: An Overview of Classification, Diagnostic Tools and Clinical Associations
Frontiers in Immunology, 2019 Nephritic factors comprise a heterogeneous group of autoantibodies against neoepitopes generated in the C3 and C5 convertases of the complement system, causing its dysregulation.
Fernando Corvillo +11 more
doaj +1 more source
Immunological features of patients affected by Barraquer-Simons syndrome
Orphanet Journal of Rare Diseases, 2020 Background C3 hypocomplementemia and the presence of C3 nephritic factor (C3NeF), an autoantibody causing complement system over-activation, are common features among most patients affected by Barraquer-Simons syndrome (BSS), an acquired form of partial ...
Fernando Corvillo +13 more
doaj +1 more source
Twisted Novikov homology of complex hypersurface complements
, 2016 We study the twisted Novikov homology of the complement of a complex hypersurface in general position at infinity. We give a self-contained topological proof of the vanishing (except possibly in the middle degree) of the twisted Novikov homology groups ...
Friedl, Stefan, Maxim, Laurentiu
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Haemolytic uremic syndrome: diagnosis and management [version 1; peer review: 3 approved]
F1000Research, 2019 The thrombotic microangiopathies (TMAs) are a group of diseases characterised by microangiopathic haemolysis, thrombocytopenia, and thrombus formation leading to tissue injury.
Neil S. Sheerin, Emily Glover
doaj +1 more source
A 1-parameter family of spherical CR uniformizations of the figure eight knot complement
, 2016 We describe a simple fundamental domain for the holonomy group of the boundary unipotent spherical CR uniformization of the figure eight knot complement, and deduce that small deformations of that holonomy group (such that the boundary holonomy remains ...
Deraux, Martin
core +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A cut above: atypical proteolysis endows complement C3 with non-canonical immune activities
The EMBO JournalWell-defined proteolysis of complement component 3 (C3) produces fragments that mediate its classic activities including target opsonization and phagocytosis. In this issue of The EMBO Journal, Demir et al, (2025) uncover a novel C3 fragment, C3-LHF1, in
Erin E West, Claudia Kemper
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source