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Preanalytical classical and alternative complement pathway activity loss [PDF]
Biochemia Medica, 2019 Introduction: Complement functional analyses provide insight into the integrity of the entire complement reaction cascade. These tests are suitable for investigating suspected complement deficiencies. Falsely reduced test outcomes may result from preanalytical instabilities of individual complement components.
Vercauteren, Koen O.A. +2 more
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Human pentraxin 3 binds to the complement regulator c4b-binding protein.
PLoS ONE, 2011 The long pentraxin 3 (PTX3) is a soluble recognition molecule with multiple functions including innate immune defense against certain microbes and the clearance of apoptotic cells.
Anne Braunschweig, Mihály Józsi
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Reducing sialylation in melanoma increases classical pathway-mediated complement activation
iScienceSummary: Strategies to reduce tumor sialylation have progressed to clinical trials, as they improved anti-tumor cellular responses in pre-clinical models.
Magali Coccimiglio +6 more
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2015 Background Activation of the complement system plays an important role in the regulation of immune and inflammatory reactions, and contributes to inflammatory responses triggered by envenomation provoked byBothrops snakes.
Lorena Rocha Ayres +7 more
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Revista Cubana de Hematología, Inmunología y Hemoterapia, 2003 The haemolytic activity of the classical and alternative pathways, of factors B and D, as well as of the levels of C1q, C3 and C4 was determined in the serum of 24 adult patients with Hodgkin disease at different clinical stages.
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Журнал микробиологии, эпидемиологии и иммунобиологииIntroduction. Complement is a key humoral participant of immunity involved in defensive and pathological processes. Human lysozyme (hLZ), hen egg white lysozyme (HEWL) and lactoferrin (LF) are classical constituents of innate immunity.
Ilia A. Krenev +6 more
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Gut Microbes ReportsAntibodies play an essential role in preserving intestinal homeostasis in healthy and dysbiotic states. Recent studies demonstrate that a microbiome-dependent intestine-specific complement system maintains intestinal homeostasis.
Nicolas Vitari +7 more
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An Excretory Protein of Echinococcus multilocularis Inhibits Complement Classical Pathway Activation
Infection and Drug Resistance, 2022 Yiwen Qiu, Shu Shen, Yi Yang, Wentao Wang Department of Liver Surgery and Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, People’s Republic of ChinaCorrespondence: Wentao Wang, Department of Liver Surgery and Liver ...
Qiu Y, Shen S, Yang Y, Wang W
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Nature Communications, 2016 C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.
Roberta Bulla +9 more
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Marine Drugs, 2008 Many biological properties of algae have been found to have useful applications in human health, particularly in the fields of oncology and immunology.
Anne Bordron +6 more
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