Results 281 to 290 of about 3,085,481 (399)

C3 glomerulopathy — understanding a rare complement-driven renal disease

Nature Reviews Nephrology, 2019
Richard J. H. Smith, G. Appel, A. Blom, H. Cook, V. D’Agati, F. Fakhouri, V. Frémeaux-Bacchi, M. Józsi, D. Kavanagh, John D Lambris, M. Noris, M. Pickering, G. Remuzzi, S. R. de Córdoba, S. Sethi, J. van der Vlag, P. Zipfel, C. Nester   +17 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

NETosis, complement, and coagulation: a triangular relationship

Cellular & Molecular Immunology, 2018
C. D. Bont, W. Boelens, G. Pruijn
semanticscholar   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

The renaissance of complement therapeutics

Nature Reviews Nephrology, 2018
Daniel Ricklin, D. Mastellos, E. Reis, John D Lambris   +3 more
semanticscholar   +1 more source

Studies of Complement-Fixing and Neutralizing Antibodies against Certain Adenoviruses [PDF]

, 1957
Sidney Katz, William S. Jordan, George F. Badger, John H. Dingle   +3 more
openalex   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani, Aditi Singh, Behnam Ashrafi   +2 more
wiley   +1 more source

A homogeneous immunoassay technology based on liposomes and the complement system enables one-step, no-wash, rapid diagnostics directly in serum. [PDF]

Anal Bioanal Chem
Hoecherl K, Streif S, Spitzenberg C, Rink S, Behrent A, Holzhausen F, Griesche C, Rogoll C, Foedlmeier M, Gebhard A, Kulikowski K, Schaefer N, Pauly D, Baeumner AJ.   +13 more
europepmc   +1 more source