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Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]
, 2010 Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H. +4 more
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Complementizer Agreement [PDF]
, 2020 This chapter discusses Complementizer Agreement (CA): agreement between the complementizer introducing an embedded finite clause and the subject of that embedded clause. CA is mainly found in Frisian and the nonstandard varieties of Dutch and German.
openaire +8 more sources
Haematologica, 2015 T follicular helper cells are the main CD4+ T cells specialized in supporting B-cell responses, but their role in driving transfusion-associated alloimmunization is not fully characterized.
Emmanuelle Godefroy +4 more
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Subspaces with a common complement in a Banach space [PDF]
, 2007 We study the problem of the existence of a common algebraic complement for a pair of closed subspaces of a Banach space. We prove the following two characterizations: (1) The pairs of subspaces of a Banach space with a common complement coincide with ...
Drivaliaris, D., Yannakakis, N.
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Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics
Pharmacological Reviews, 2021 The complement system was discovered at the end of the 19th century as a heat-labile plasma component that “complemented” the antibodies in killing microbes, hence the name “complement.” Complement is also part of the innate immune system, protecting the
P. Garred, A. Tenner, T. Mollnes
semanticscholar +1 more source
Molecular Immunology, 2011 The brain is considered to be an immune privileged site, because the blood-brain barrier limits entry of blood borne cells and proteins into the central nervous system (CNS). As a result, the detection and clearance of invading microorganisms and senescent cells as well as surplus neurotransmitters, aged and glycated proteins, in order to maintain a ...
Veerhuis, Robert +2 more
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Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis
mBio, 2018 The complement system is a critical part of host defense to many bacterial, viral, and fungal infections. It works alongside pattern recognition receptors to stimulate host defense systems in advance of activation of the adaptive immune response. In this
Lisa E. Gralinski +8 more
semanticscholar +1 more source
Learning to Complement Humans [PDF]
International Joint Conference on Artificial Intelligence, 2020 A rising vision for AI in the open world centers on the development of systems that can complement humans for perceptual, diagnostic, and reasoning tasks.
Bryan Wilder, E. Horvitz, Ece Kamar
semanticscholar +1 more source
Frontiers in Microbiology, 2017 Leptospirosis is a zoonosis caused by spirochetes from the genus Leptospira. This disease is common in tropical and subtropical areas, constituting a serious public health problem.
Thais A. Amamura +4 more
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Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
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