Results 31 to 40 of about 1,441,098 (322)
A Review of Complement Activation in SLE
Current Rheumatology Reports, 2021 Purpose of Review Complement activation is a key event in the pathogenesis of tissue inflammation and injury in systemic lupus erythematosus (SLE). This review is aimed at comparing the usefulness of measurement of complement proteins in serum/plasma (C3,
A. Weinstein, R. Alexander, D. Zack
semanticscholar +1 more source
Symmetries and hidden symmetries of $(ε, d_L)$-twisted knot complements [PDF]
Algebr. Geom. Topol. 22 (2022) 601-656, 2019 In this paper we analyze symmetries, hidden symmetries, and commensurability classes of $(\epsilon, d_L)$-twisted knot complements, which are the complements of knots that have a sufficiently large number of twists in each of their twist regions. These knot complements can be constructed via long Dehn fillings on fully augmented links complements.
arxiv +1 more source
Frontiers in Immunology, 2022 Components of the extracellular matrix (ECM), when exposed to body fluids may promote local complement activation and inflammation. Pathologic complement activation at the glomerular basement membrane and at the Bruch’s membrane is implicated in renal ...
Alexandra Papp +16 more
doaj +1 more source
Complement in neurological disorders and emerging complement-targeted therapeutics
Nature Reviews Neurology, 2020 The complement system consists of a network of plasma and membrane proteins that modulate tissue homeostasis and contribute to immune surveillance by interacting with the innate and adaptive immune systems.
M. Dalakas, H. Alexopoulos, P. Spaeth
semanticscholar +1 more source
Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions
Journal for ImmunoTherapy of Cancer, 2020 Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response.
Diane Damotte +20 more
doaj +1 more source
Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization
Haematologica, 2016 Transfusions are the main treatment for patients with sickle cell disease. However, alloimmunization remains a major life-threatening complication for these patients, but the mechanism underlying pathogenesis of alloimmunization is not known.
Emmanuelle Godefroy +7 more
doaj +1 more source
Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration
Science, 2005 Age-related macular degeneration (AMD) is a leading cause of visual impairment and blindness in the elderly whose etiology remains largely unknown. Previous studies identified chromosome 1q32 as harboring a susceptibility locus for AMD.
J. Haines +13 more
semanticscholar +1 more source
Complementation of Subquandles [PDF]
arXiv, 2023 Saki and Kiani proved that the subrack lattice of a rack $R$ is necessarily complemented if $R$ is finite but not necessarily complemented if $R$ is infinite. In this paper, we investigate further avenues related to the complementation of subquandles.
arxiv
Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low Monocytes
Cell Reports, 2015 Monocytes are heterogeneous effector cells involved in the maintenance and restoration of tissue integrity. However, their response to hyperlipidemia remains poorly understood.
Maha F. Saja +9 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2005 Age-related macular degeneration (AMD) is the most frequent cause of irreversible blindness in the elderly in developed countries. Our previous studies implicated activation of complement in the formation of drusen, the hallmark lesion of AMD.
semanticscholar +1 more source