Results 221 to 230 of about 49,543 (282)

Integrative chromosome‐scale genome analysis of cupuassu provides insights into witches' broom disease resistance and expands genomic resources for Theobroma

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Cupuassu (Theobroma grandiflorum) is a fruit tree native to the Brazilian Amazon and increasingly relevant to regional bioeconomies. Its cultivation is severely affected by witches’ broom disease (WBD), caused by Moniliophthora perniciosa. While a chromosome‐scale genome of the susceptible genotype C1074 is available, the lack of a resistant ...
Vinicius A. C. de Abreu, Rafael Moysés Alves, Mauro de Medeiros Oliveira, Vitor Trinca, Loeni Ludke Falcão, Lucilia Helena Marcellino, Antonio Figueira, Douglas S. Domingues, Alessandro M. Varani   +8 more
wiley   +1 more source

Evaluating functional C1INH with multiple laboratory methods across Hereditary Angioedema types. [PDF]

Front Immunol
Bardou MLD, Constantino-Silva RN, Alonso MLO, Teixeira AJR, Giavina-Bianchi PF, Mansour E, Pesquero JB, Valle SOR, Grumach AS.   +8 more
europepmc   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

Inhibition of FXIIa attenuates kidney fibrosis in mice with unilateral ureteral obstruction. [PDF]

Cell Mol Life Sci
Kalina D, Potaczek DP, Zeng-Brouwers J, Boehm M, Nolte MW, Bielohuby M, Schermuly RT, Schaefer L, Wygrecka M.   +8 more
europepmc   +1 more source

Generation of Mice Harboring Bicc1 Conditional Null Alleles

genesis, Volume 64, Issue 1, February 2026.
ABSTRACT Bicaudal C1 (Bicc1) encodes an RNA‐binding protein critical for many organ development and epithelial tissue homeostasis. Bicc1 null mutations have been shown to lead to the development of polycystic kidney disease (PKD) and death at an early prenatal stage.
Chia‐Feng Liu, Steven Leon, Isabella Herrig, Oliver Wessely, W. H. Wilson Tang   +4 more
wiley   +1 more source

Triply Responsive Control of Ion Transport with an Artificial Channel Creates a Switchable AND to OR Logic Gate

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
We report a triply responsive artificial ion channel, showing tuneable activity, and responsive to three distinct stimuli ‐ light, pH, and ligand – which we use to formulate an AND to OR switchable molecular logic gate. Abstract Ion channels are ubiquitous in Nature, performing complex and essential tasks in our bodies. Synthetic chemists have begun to
Javid Ahmad Malla, Kharina J. Fenton, Adinarayana Bellamkonda, Samuel I. Fidler, Mark I. Wallace, Charlie T. McTernan   +5 more
wiley   +2 more sources

A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice. [PDF]

Nat Commun
Zhang Y, Watson B, Rattan A, Lee T, Chawla S, Geistlinger L, Guan Y, Lord FB, Ma M, Miwa T, Golla M, Caldarone BJ, Song WC, Moffitt JR, Carroll MC.   +14 more
europepmc   +1 more source

The Factors Involved in Plant–Insect–Microbe Interactions Expanded: Genome Analysis and Description of Frigoribacterium adelgis sp. nov.

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Aerobic Actinobacteria belonging to the genus Frigoribacterium were isolated from adelgid Adelges (Aphrastasia) pectinatae collected from a Korean fir tree. Genomic analysis showed that these bacteria encode a range of factors that may be involved in the interactions between Frigoribacterium strains, adelgids and/or Korean fir trees.
Gustė Tamošiūnaitė, Jekaterina Havelka, Raimonda Baranauskienė, Justas Lazutka, Nomeda Kuisiene   +4 more
wiley   +1 more source

Sepsis-Induced Endothelial Barrier Dysfunction: Mechanisms, Pathology, and Therapeutic Advances. [PDF]

Research (Wash D C)
Wang R, Han Q, Fan J, Xu Z, Liu W, Liu D, Li Y, Du J, Sun J, Zhang H, Cai Q, Gao C, Jiang J, Wang Z, Zeng L.   +14 more
europepmc   +1 more source

Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Mutations in GNAO1, the gene encoding Gαo, are associated with a wide range of neurodevelopmental disorders. In this study, we show that Gαo variants linked to the most severe patient phenotypes fail to disengage from activated Gi/o‐coupled GPCRs, thereby blocking GRK‐mediated receptor phosphorylation and internalization.
Yonika A. Larasati, Camille Rabesahala de Meritens, Miriam Stoeber, Vladimir L. Katanaev, Gonzalo P. Solis   +4 more
wiley   +1 more source