Results 231 to 240 of about 48,228 (282)

Complement Cascades and Brain Disorders. [PDF]

Biomolecules
Jovčevska I, Videtič Paska A, Kouter K.   +2 more
europepmc   +1 more source

Outer Membrane Vesicles Mediate the Secretion and Nuclear Trafficking of a Bacterial Nucleomodulin

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
(A) We propose that Helicobacter pylori secretes a nucleomodulin, Tumour Necrosis Factor‐α‐inducing protein (Tipα), predominantly via extracellular vesicles (EVs), also known as outer membrane vesicles, rather than as free protein. (B) EVs carrying Tipα enter eukaryotic cells by endocytosis and independently of surface‐expressed nucleolin, then traffic
Jack K. Emery, Variya Nemidkanam, Nina Colon, Kate R. J. Friesen, Lena H. M. Le, Angus R. Cramond, Maxine Yap, Mônica S. Barbosa, Georgie Wray‐McCann, David J. McGee, Natalia Castaño‐Rodríguez, Dongmei Tong, Caroline Skene, Laurent Terradot, Richard L. Ferrero   +14 more
wiley   +1 more source

The Complement System in ANCA-Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs. [PDF]

Immun Inflamm Dis
Sunmboye K, Millan P.
europepmc   +1 more source

Acquired Angioedema Associated With Systemic Lupus Erythematosus Presenting as Acute Abdomen: A Case Report

Journal of General and Family Medicine, Volume 27, Issue 3, May 2026.
ABSTRACT Acquired angioedema (AAE) due to C1 inhibitor deficiency can present as acute abdomen. A 24‐year‐old woman developed severe abdominal pain and bowel wall edema initially suggestive of hereditary angioedema, but genetic testing excluded it. She later manifested fever, arthritis, rash, and serological abnormalities consistent with systemic lupus
Seiji Shiota, Shogo Kodama, Kouichirou Tahara   +2 more
wiley   +1 more source

Activation of the Complement/Lectin Pathway, Angiopoietin/Tie-2/VEGF-System, Cytokines and Chemokines in Different Angioedema Subtypes. [PDF]

Eur J Immunol
Duda KM, Gehring M, Wedi B.
europepmc   +1 more source

Complement in brain and eye disease: shared mechanisms, convergent pathologies, and common therapeutic opportunities. [PDF]

Mamm Genome
Nimmo J, Bright M, Yang Z, Nicholls LE, Morgan BP, Daskoulidou N, Daskoulidou N, Zelek WM.   +7 more
europepmc   +1 more source

Unexpected genomic architecture in a sporadic case of C1-INH Hereditary Angioedema: the hidden heritability. [PDF]

Orphanet J Rare Dis
Marchionni E, Mannucci L, Di Tommaso S, Nardone AM, Albanese M, Novelli A, Sangiuolo FC, Triggianese P, Novelli G.   +8 more
europepmc   +1 more source

Complement role in kidney disease: a comprehensive review and therapeutic innovations. [PDF]

BMC Nephrol
Cortez Ferreira B, Matos Silva G, Venda J, Afonso N, Leal R, Cerqueira S, Galvão A, Sá H.   +7 more
europepmc   +1 more source

Targeting C1q signaling in fibro-adipogenic progenitors prevents regenerative fibrosis of aged muscle. [PDF]

Proc Natl Acad Sci U S A
Kanugovi A, Aguiari P, Choi R, Kim S, Wu D, De Morree A, Bui S, Lam R, Biressi S, Liu L, Rando TA.   +10 more
europepmc   +1 more source