Results 71 to 80 of about 65,236 (304)

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Hereditary angioedema: a disease seldom diagnosed by pediatricians

Jornal de Pediatria, 2021
Objectives: To describe the hereditary angioedema to improve awareness of this condition and reduce diagnostic delay. Data sources: Relevant articles in the MEDLINE database through PubMed.
Régis de Albuquerque Campos, Solange Oliveira Rodrigues Valle, Eliana Cristina Toledo   +2 more
doaj   +1 more source

ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]

, 2005
Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
core   +2 more sources

Functional Materials for Environmental Energy Harvesting in Smart Agriculture via Triboelectric Nanogenerators

Advanced Functional Materials, EarlyView.
This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva, Giulio Fatti, Emanuel Carlos, Guilherme Ferreira, Sumita Goswami, Suman Nandy, Luiz H. C. Mattoso, Elvira Fortunato, Caio G. Otoni, Rodrigo Martins   +9 more
wiley   +1 more source

Overview of SERPING1 Variations Identified in Hungarian Patients With Hereditary Angioedema

Frontiers in Allergy, 2022
BackgroundHereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency (C1-INH-HAE) is a rare autosomal dominant disorder, characterized by recurrent, unpredictable edematous symptoms involving subcutaneous, and/or submucosal tissue.
Edina Szabó, Dorottya Csuka, Noémi Andrási, Noémi Andrási, Noémi Andrási, Lilian Varga, Henriette Farkas, Henriette Farkas, Ágnes Szilágyi   +8 more
doaj   +1 more source

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC‐Derived Liver Progenitor Cell Differentiation

Advanced Healthcare Materials, EarlyView.
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain, Brock Grenci, Hyeon Ryoo, Yang Yuan, Salman R. Khetani, Gregory H. Underhill   +5 more
wiley   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

MS-proteomics provides insight into the host responses towards alginate microspheres

Materials Today Bio, 2022
Protein adsorption to biomaterial surfaces is considered a determining factor for the host response. Here we detail the protein adsorption profiles of alginate hydrogel microspheres relevant for cell therapy using mass spectrometry (MS)-based proteomics.
Abba E. Coron, Davi M. Fonseca, Animesh Sharma, Geir Slupphaug, Berit L. Strand, Anne Mari A. Rokstad   +5 more
doaj   +1 more source

Managing Diagnosis, Treatment, and Burden of Disease in Hereditary Angioedema Patients with Normal C1-Esterase Inhibitor

Journal of Asthma and Allergy, 2023
Douglas Jones,1 Heidi Zafra,2 John Anderson3 1Rocky Mountain Allergy, Tanner Clinic, Layton, UT, USA; 2Division of Allergy and Clinical Immunology, Medical College of Wisconsin, Milwaukee, WI, USA; 3AllerVie Health, Birmingham, AL, USACorrespondence ...
Jones D, Zafra H, Anderson J
doaj  

Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins. [PDF]

, 2019
Dinoflagelates and cyanobacteria produce saxitoxin (STX), a lethal bis-guanidinium neurotoxin causing paralytic shellfish poisoning. A number of metazoans have soluble STX-binding proteins that may prevent STX intoxication.
Du Bois, J, Lolicato, Marco, Minor, Daniel L, Thomas-Tran, Rhiannon, Yen, Tien-Jui   +4 more
core   +2 more sources