Results 101 to 110 of about 23,738 (171)

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Long‐term remission of type B insulin resistance syndrome with immunotherapy: A case report

Journal of Diabetes Investigation, Volume 17, Issue 3, Page 542-545, March 2026.
ABSTRACT We report long‐term remission in a patient with type B insulin resistance achieved with a combination of immunotherapies. A 55‐year‐old Japanese man presented with nocturnal hypoglycemia and cytopenia. He also had postprandial hyperglycemia due to severe insulin resistance, which was difficult to manage using high‐dose insulin and recombinant ...
Erika Egawa, Rei Karasawa, Yuka Kageyama, Kazuhiko Takaya   +3 more
wiley   +1 more source

Proangiogenic properties of complement protein C1q can contribute to endometriosis

Frontiers in Immunology
Endometriosis (EM) is defined as the engraftment and proliferation of functional endometrial-like tissue outside the uterine cavity, leading to a chronic inflammatory condition.
Chiara Agostinis, Miriam Toffoli, Gabriella Zito, Andrea Balduit, Silvia Pegoraro, Mariagiulia Spazzapan, Lorella Pascolo, Federico Romano, Giovanni Di Lorenzo, Alessandro Mangogna, Aurora Santin, Beatrice Spedicati, Beatrice Spedicati, Erica Valencic, Giorgia Girotto, Giorgia Girotto, Giuseppe Ricci, Giuseppe Ricci, Uday Kishore, Uday Kishore, Roberta Bulla   +20 more
doaj   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Complement C1q essential for aeroallergen sensitization via CSF1R⁺ conventional dendritic cells type 2. [PDF]

J Allergy Clin Immunol, 2023
Moon HG, Eccles JD, Kim SJ, Kim KH, Kim YM, Rehman J, Lee H, Kanabar P, Christman JW, Ackerman SJ, Ascoli C, Kang H, Choi HS, Kim M, You S, Park GY.   +15 more
europepmc   +1 more source

Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality. [PDF]

Front Immunol, 2022
Trzeciak A, Mongre RK, Kim MR, Lim K, Madero RA, Parkhurst CN, Pietropaoli AP, Kim M.   +7 more
europepmc   +1 more source

Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma. [PDF]

Ophthalmol Sci, 2023
Sun Y, Wirta D, Murahashi W, Mathur V, Sankaranarayanan S, Taylor LK, Yednock T, Fong DS, Goldberg JL.   +8 more
europepmc   +1 more source

Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models. [PDF]

Nat Aging, 2022
Dejanovic B, Wu T, Tsai MC, Graykowski D, Gandham VD, Rose CM, Bakalarski CE, Ngu H, Wang Y, Pandey S, Rezzonico MG, Friedman BA, Edmonds R, De Mazière A, Rakosi-Schmidt R, Singh T, Klumperman J, Foreman O, Chang MC, Xie L, Sheng M, Hanson JE.   +21 more
europepmc   +1 more source

Elevated Serum Complement C1q Levels After Traumatic Brain Injury [Letter]. [PDF]

Neuropsychiatr Dis Treat, 2022
Paiva WS, Ortiz J, Amorim RL.
europepmc   +1 more source

Circulating Complement C1q as a Novel Biomarker is Associated with the Occurrence and Development of COPD. [PDF]

Int J Chron Obstruct Pulmon Dis, 2022
Zhang K, Han K, Liu H, Zheng C.
europepmc   +1 more source