Results 101 to 110 of about 40,238 (270)
Journal of Clinical Laboratory Analysis, EarlyView.Raised anti‐C1q antibody titres in South Africans with SLE were associated with active LN, as evidenced by an active urine sediment. A positive anti‐C1q antibody and low serum C1q were associated with a positive Direct Coombs' test. ABSTRACT Objective To investigate prevalence and clinical correlates of serum C1q and anti‐C1q antibody titres in black ...
Mohammed Tikly +2 more
wiley +1 more source
Engineering Efferocytosis for Bone Regeneration
Macromolecular Bioscience, EarlyView.The repair of bone tissue in acute and chronic injuries is a significant long‐standing clinical challenge. Biomaterials‐based interventions are well‐positioned to interrogate mechanisms of efferocytosis due to their ability to provide support and guide cellular activity.
Jacob Miszuk, Linna Zhong, Hongli Sun
wiley +1 more source
Huntington's disease: An immune perspective [PDF]
, 2011 Copyright © 2011 Annapurna Nayaketal. This article has been made available through the Brunel Open Access Publishing Fund.Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide ...
Ansar, R +4 more
core +3 more sources
Bio-Protocol, 2014 In situ hybridization and immunostaining are common techniques for localizing gene expression, the mRNA and protein respectively, within tissues. Both techniques can be applied to tissue sections to achieve similar goals, but in some cases, it is ...
Manuel Lopez
doaj +1 more source
Recent Advancements in the Treatment of Age‐Related Macular Degeneration
Med Research, EarlyView.ABSTRACT Age‐related macular degeneration (AMD) is a prevalent cause of visual impairment and blindness among the elderly. AMD can be categorized into two subtypes: “wet” and “dry.” Current treatments for wet AMD mainly involve anti‐vascular endothelial growth factor (VEGF) drugs, and there are three U.S.
Shan Liu +10 more
wiley +1 more source
Frontiers in ImmunologyHelminths produce calreticulin (CRT) to immunomodulate the host immune system as a survival strategy. However, the structure of helminth-derived CRT and the structural basis of the immune evasion process remains unclarified. Previous study found that the
Zhihui Jia +11 more
doaj +1 more source
Causal Link and Shared Biomarkers Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis
Med Research, EarlyView.ABSTRACT This study investigates the causal relationship between rheumatoid arthritis (RA) and idiopathic pulmonary fibrosis (IPF), aiming to identify shared biomarkers between the two conditions. Utilizing bidirectional Mendelian randomization (MR), we assessed causality by analyzing genome‐wide association study (GWAS) data from European cohorts ...
Xixi Pan +5 more
wiley +1 more source
Anti-C1q antibodies as a follow-up marker in SLE patients.
PLoS ONE, 2015 In cross-sectional studies autoantibodies against complement C1q (anti-C1q) were found to be highly associated with active lupus nephritis. The aim of this retrospective study was to determine the value of anti-C1q as follow-up marker of disease activity
Merete Bock +2 more
doaj +1 more source
HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis [PDF]
, 2017 Background Abnormal activation of the complement system contributes to some central nervous system diseases but the role of complement in HIV-associated neurocognitive disorder (HAND) is unclear.
Borjabad, Alejandra +8 more
core +2 more sources
Neuroprotection, EarlyView.Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal +2 more
wiley +1 more source