Elevated Serum Complement C1q Levels After Traumatic Brain Injury [Letter]. [PDF]
Neuropsychiatr Dis Treat, 2022 Paiva WS, Ortiz J, Amorim RL.
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Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome
Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5463-5475, July 2026.ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler +4 more
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Circulating Complement C1q as a Novel Biomarker is Associated with the Occurrence and Development of COPD. [PDF]
Int J Chron Obstruct Pulmon Dis, 2022 Zhang K, Han K, Liu H, Zheng C.
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The FEBS Journal, Volume 293, Issue 13, Page 3848-3864, July 2026.Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki +4 more
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Prognostic and immune-related value of complement C1Q (C1QA, C1QB, and C1QC) in skin cutaneous melanoma. [PDF]
Front Genet, 2022 Yang H, Che D, Gu Y, Cao D.
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Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
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Association of serum complement C1q with cardiovascular outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention. [PDF]
J Geriatr Cardiol, 2022 Li QX +8 more
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Xenotransplantation, Volume 33, Issue 4, July/August 2026.ABSTRACT Inflammatory responses have been shown to contribute significantly to the rejection of grafts in both allo‐ and xenotransplantation. In particular, they play a pivotal role in promoting endothelial activation, complement deposition, and thrombosis, thereby compromising the graft function.
Mitra Gultom +8 more
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Association of Serum Complement C1q and C3 Level with Age-Related Macular Degeneration in Women. [PDF]
J Inflamm Res, 2022 Ma Y +6 more
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Blockade of Type 2A Protein Phosphatase Signaling Attenuates Complement C1q-Mediated Microglial Phagocytosis of Glutamatergic Synapses Induced by Amyloid Fibrils. [PDF]
Mol Neurobiol, 2023 Wu J, Xu J, Naguib M, Bie B.
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