B Cell Subsets and Atherosclerosis: Updates and Emerging Concepts
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) is increasingly recognized not just as a lipid‐driven disease, but as a complex interplay between vascular cells and the immune system. Accumulating evidence highlights a central, yet heterogeneous role for B cells in atherogenesis, with distinct subsets displaying opposing roles.
Sophieke Lems +3 more
wiley +1 more source
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models. [PDF]
Dejanovic B +21 more
europepmc +1 more source
Galectin-3 – A novel ligand of complement protein C1q
In the present study we report a novel interaction of human C1q, a primary activator of the Complement system, with human Galectin-3 (Gal-3). We investigated the potential recognition between C1q and Gal-3 on a solid hydrophobic surface by ELISA, by fluorescence spectroscopy, molecular docking and molecular dynamics (MD).
Gabriela Radulova +6 more
openaire +2 more sources
Elevated Serum Complement C1q Levels After Traumatic Brain Injury [Letter]. [PDF]
Paiva WS, Ortiz J, Amorim RL.
europepmc +1 more source
Circulating Complement C1q as a Novel Biomarker is Associated with the Occurrence and Development of COPD. [PDF]
Zhang K, Han K, Liu H, Zheng C.
europepmc +1 more source
Prognostic and immune-related value of complement C1Q (C1QA, C1QB, and C1QC) in skin cutaneous melanoma. [PDF]
Yang H, Che D, Gu Y, Cao D.
europepmc +1 more source
Association of serum complement C1q with cardiovascular outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention. [PDF]
Li QX +8 more
europepmc +1 more source
Blockade of Type 2A Protein Phosphatase Signaling Attenuates Complement C1q-Mediated Microglial Phagocytosis of Glutamatergic Synapses Induced by Amyloid Fibrils. [PDF]
Wu J, Xu J, Naguib M, Bie B.
europepmc +1 more source

