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Structure-function studies of the receptors for complement C1q
Biochemical Society Transactions, 2002C1q is an essential component of the phylo-genetically ancient innate complement (C) system and is crucial to our natural ability to ward off infection and clear toxic cell debris (e.g. amyloid fibrils, apoptotic cells). Several candidate C1q receptors [C1q receptor for phagocytosis enhancement (C1qRp), complement receptor (CR) 1, calreticulin (CRT ...
E, McGreal, P, Gasque
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Complement protein C1q induces maturation of human dendritic cells
Molecular Immunology, 2007Maturation of dendritic cells (DCs) is known to be induced by several stimuli, including microbial products, inflammatory cytokines and immobilized IgG, as demonstrated recently. Since immune complexes formed in vivo also contain C1q, moreover apoptotic cells and several pathogens fix C1q in the absence of antibodies, we undertook to investigate ...
Cosmor, E +6 more
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Interaction of plasma fibronectin with gelatin and complement C1q
Molecular Immunology, 1983A variety of techniques have been used to examine the interaction of human plasma fibronectin (Fn) with complement C1q in comparison to that with gelatin in phosphate buffered saline at pH 7.4. The precipitation of 3H-Fn by polyethylene glycol (PEG) was shifted to much lower concentrations of the polymer by addition of gelatin, and to a lesser extent ...
K C, Ingham, S A, Brew, S I, Miekka
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Activation of Mammalian Complement by Chicken C1q
1983Activation of chicken complement by the classical pathway is still debatable. Both positive and negative evidence of antibody dependent lysis has been reported. The components from C3 to C9 function since activation via the alternative pathway will lyse mammalian erythrocytes in the absence of Ig.
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Biochemical Specificity of Human Complement Component C1q
1983The serum complement system has an important role in host defense and haemostasis, and inflammatory processes1. It consists of 9 components, 2 factors and 9 regulatory processes2,3. With the exception of factor D, the complement proteases circulate in vivo as zymogens which are activated to a system of interacting transiently active proteases by ...
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Autoantibodies against complement C1q specifically target C1q bound on early apoptotic cells
Molecular Immunology, 2008Cornelia Bigler +3 more
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C1q protein of human complement.
Biochemistry, 1972M A, Calcott, H J, Müller-Eberhard
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4882423 Substance-conjugated complement component C1Q
Comparative Immunology, Microbiology and Infectious Diseases, 1990openaire +1 more source
[Complement subcomponent C1q in rheumatic diseases].
Ryumachi. [Rheumatism], 1987K, Yonemasu, T, Sasaki
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