Results 91 to 100 of about 74,672 (291)

Genomic organization of human complement component C3

Genomics, 1990
Six overlapping clones, spanning the entire C3 gene and the 5' flanking region, were isolated from two genomic lambda libraries. Thirty exons, covering the complete beta chain and part of the alpha chain as far as the C3d region, were analyzed.
Marina Botto, A. K. So, Mark Walport, Kok Yong Fong   +3 more
openaire   +3 more sources

Electrochemical Chemo‐ and Regioselective Heterofunctionalization of Tropones via C(sp2)H Derivatization

Advanced Synthesis &Catalysis, EarlyView.
Simple and selective. The electrochemical heterofunctionalization of activated tropones is achieved using readily available inorganic salts. A theoretical model, based on cyclic voltammetry and quantum chemistry calculations, predicts both reactivity trends and site selectivity.
Mauro Garbini, Samuele Moncullo, Sofia Kiriakidi, Manuela Melucci, Sara Bellini, Chiara Zanardi, Carlos Silva López, Giulio Bertuzzi, Marco Bandini   +8 more
wiley   +1 more source

Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase.

PLoS Pathogens, 2017
The complement cascade is crucial for clearance and control of invading pathogens, and as such is a key target for pathogen mediated host modulation. C3 is the central molecule of the complement cascade, and plays a vital role in opsonization of bacteria
Nicola N Lynskey, Mark Reglinski, Damien Calay, Matthew K Siggins, Justin C Mason, Marina Botto, Shiranee Sriskandan   +6 more
doaj   +1 more source

Polyoxometalate Imide‐Linked Molecules, Covalent Organic Polymers, and Frameworks: Dimensionality Effects on Supercapacitors Performance

Advanced Sustainable Systems, EarlyView.
This study explores polyoxometalate‐based hybrids with varying dimensionalities, linking molecular, polymeric, and framework structures to supercapacitor performance. The results highlight how structural tuning enhances surface area, porosity, and charge transport, offering insights into designing efficient energy storage materials.
Daria Nowicka, Verónica Montes‐García, Aleksandra Sikora, Violetta Patroniak, Adam Gorczyński, Dawid Pakulski, Artur Ciesielski   +6 more
wiley   +1 more source

Complement Activation in Semisolid Media: Insolubilization of Alternative Pathway Convertases in Agar Gels with C3 Nephritic Factor-Containing Sera [PDF]

, 1977
Mohammed A. Arnaout, Alvin E. Davis, Fred S. Rosen, Chester A. Alper   +3 more
openalex   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Demonstration of Binding Sites for IgG Fc and the Third Complement Component (C3) on Isolated Hepatocytes [PDF]

, 1976
U. Hopf, Karl‐Hermann Meyer zum Büschenfelde, Manfred P. Dierich   +2 more
openalex   +1 more source

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

Advanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio‐Lopez, Douglas Hazel, Michael Levin   +6 more
wiley   +1 more source

Requirements for the solubilization of immune aggregates by complement: assembly of a factor B-dependent C3-convertase on the immune complexes. [PDF]

, 1977
M Takahashi, Brian F. Tack, Victor Nussenzweig   +2 more
openalex   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source