Advanced Science, EarlyView.This study primarily reveals that PM2.5‐derived Fe‐containing particles, particularly magnetite, are specifically enriched in the heart. Here, they interact with NCOA4 in endothelial cells, disrupt iron homeostasis by enhancing ferritinophagy, and subsequently trigger the process of EndMT through the NCOA4/KLF5 pathway.
Qinglin Sun +11 more
wiley +1 more source
Monoclonal antibodies against complement 3 neoantigens for detection of immune complexes and complement activation. Relationship between immune complex levels, state of C3, and numbers of receptors for C3b. [PDF]
, 1985 M. Teresa Aguado +7 more
openalex +1 more source
Advanced Science, EarlyView.The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan +5 more
wiley +1 more source
Biosynthesis of the third component of complement (C3) by the human monocytic-cell line U-937 Induction by phorbol myristate acetate [PDF]
, 1986 S Bengio +4 more
openalex +1 more source
Advanced Science, EarlyView.An electro–magnetic–porous multigradient nanofibrous electromagnetic interference (EMI) membrane is fabricated via shear‐induced in situ fibrillation and layer‐by‐layer assembly. Leveraging a multigradient‐induced “impedance matching–polarization–reabsorption” synergistic mechanism, the membrane achieves absorption‐dominated high‐efficiency EMI ...
Runze Shao +5 more
wiley +1 more source
Electric Field‐Stimulated Autofluorescence for In Situ 3D Characterization of Polymer Defects
Advanced Science, EarlyView.Moderate electric fields induce intrinsic autofluorescence at microscale defects within diverse polymers under laser excitation. Combined with confocal microscopy, this probe‐free method enables real‐time, submicron‐resolution 3D imaging of voids, fillers, and electrical trees before irreversible damage occurs.
Chaolu Niu +8 more
wiley +1 more source
Chemical evidence for common genetic ancestry of complement components C3 and C5.
, 1977 H N Fernandez, T E Huglij
openalex +1 more source
Characterization of the initial C3 convertase of the alternative pathway of human complement. [PDF]
, 1984 Zvi Fishelson +2 more
openalex +1 more source
Direct Carboboration of Aryl Alkenes with Stable Organoborons Through Ziegler‐Type Addition
Advanced Science, EarlyView.The direct carboboration of vinyl arenes with benzylic boronates has been achieved using KOtBu as the catalyst. Vinylcyclopropanes and vinylcyclobutane also participate in this reaction, yielding the corresponding 1,5‐ and 1,6‐carboboration products.
Mo Yang +5 more
wiley +1 more source
Complement C3 in serum and plasma, as measured by radial immunodiffusion with four commercial kits.
, 1976 A O Vladutiu, B M Winiarski
openalex +1 more source