Results 251 to 260 of about 264,280 (300)

Potentiating CD20 monoclonal antibody therapy by targeting complement C3 fragments covalently deposited on lymphoma cells.

open access: yesBlood
Baskar S   +21 more
europepmc   +1 more source

Inhibition of complement C3 prevents osteoarthritis progression in guinea pigs by blocking STAT1 activation. [PDF]

open access: yesCommun Biol
Xu JX   +6 more
europepmc   +1 more source

Complement C3-targeted therapy in C3 glomerulopathy, a prototype of complement-mediated kidney diseases

Seminars in Immunology, 2022
C3 glomerulopathy (C3G) is a rare and complex kidney disease that primarily affects young adults. Renal outcomes remain poor in the absence of specific treatment. C3G is driven by uncontrolled overactivation of the alternative complement pathway, which is mainly of acquired origin.
Marie-Sophie, Meuleman   +2 more
openaire   +2 more sources

Complement inhibition in C3 glomerulopathy

Seminars in Immunology, 2016
C3 glomerulopathy (C3G) describes a spectrum of glomerular diseases defined by shared renal biopsy pathology: a predominance of C3 deposition on immunofluorescence with electron microscopy permitting disease sub-classification. Complement dysregulation underlies the observed pathology, a causal relationship that is supported by well described studies ...
Carla M, Nester, Richard J H, Smith
openaire   +2 more sources

Complement C3 proteins in psoriasis

British Journal of Dermatology, 1989
A new polymorphism of the complement factor C3 in human plasma was demonstrated by isotachophoresis in agarose gels followed by immunodetection with rabbit anti-human C3c and C3d immunoglobulins. Four bands were detected in the immunoprint of freshly drawn EDTA-plasma, which were C3s1, C3s2, C3f1 and C3f2. At least four additional C3 components in Mg2+
F, Acevedo, H, Hammar
openaire   +2 more sources

Complement C3 in Bernese Mountain dogs

Veterinary Clinical Pathology, 2010
Background:Previous research suggests that low serum concentrations of the third component of complement (C3) are associated with both the susceptibility to infectious agents such asBorrelia burgdorferiand the development of glomerular disease. We hypothesized that low levels of C3 are associated with the coincident occurrence ofB. burgdorferiinfection
Gerber, Bernhard   +4 more
openaire   +3 more sources

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