Results 261 to 270 of about 264,280 (300)
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Inherited complement C3 deficiency: A defect in C3 secretion
European Journal of Immunology, 1994AbstractThe molecular basis of inherited complement C3 deficiency in a 20‐year‐old newly diagnosed male patient was studied. Using an enzyme‐linked immunosorbent assay, the patient's C3 serum level was found to be approximately 7 μg/ml, which is less than 1 % of normal.
Y, Katz +4 more
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Complement C3 receptors: Structure and function
Molecular Immunology, 1984Significant progress has been made during the past few years toward elucidating the structure and function of various C3 receptors. Better understanding of the biochemical basis of the immune adherence phenomenon has been achieved. The availability of polyclonal and monoclonal antibodies to C3 receptors allowed more accurate studies of the cellular ...
M A, Arnaout, H R, Colten
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Complement C3 isoforms in Austrelaps superbus
Toxicon, 2008Complement C3 plays a pivotal role in both classical and alternate pathways. Lower organisms (urochordates and fishes) have multiple isoforms whereas higher organisms have a single C3 gene. In cobras, a closely related protein cobra venom factor (CVF) is expressed in their venom gland.
Syed, Rehana, R Manjunatha, Kini
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Treatment of C3 Glomerulopathy with Complement Blockers
Seminars in Thrombosis and Hemostasis, 2014C3 glomerulopathy (C3G) is a newly defined clinical entity comprising glomerular lesions with predominant C3 staining. Under this definition are now included membranoproliferative glomerulonephritis type II (dense deposit disease) and C3 glomerulonephritis.
Marina, Vivarelli, Francesco, Emma
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C3 glomerulopathy: A new complement-based entity
Revista Clínica Española (English Edition), 2014C3 glomerulopathy is a new, recently described entity that has changed the perspective, treatment and classification of a number of glomerular diseases. It encompasses 2 similar but clearly differentiated pathologies -the dense-deposit disease and C3 glomerulonephritis itself.
A, de Lorenzo +3 more
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C3 and C6 Complement Types in Schizophrenia
Human Heredity, 1985C3 and C6 complement types were studied in schizophrenic patients and controls. The distributions of the three common C3 types (F, FS and S) among the patients was significantly different from that in the controls (p less than 0.005) and the frequency of the C3F gene was significantly increased (p less than 0.0005) among the patients.
C, Rudduck +3 more
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Interaction of Fibronectin with Complement Component C3
Scandinavian Journal of Immunology, 1983The activation of the complement component C3 generates C3a and C3b fragments, and the physiological cleavage of C3b further yields C3c and C3d fragments. We studied here by enzyme immunoassay the ability of human plasma fibronectin to interact with native C3 of human sera and with isolated C3c and C3d fragments of C3.
A, Hautanen, J, Keski-Oja
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Complement (C3)-Activated Phagocytosis by Lung Macrophages
The Journal of Immunology, 1978Abstract We have investigated the interaction between rabbit lung macrophages and Escherichia coli lipopolysaccharide-coated oil droplets opsonized with a fragment of C3, and of albumin-coated oil droplets opsonized with anti-albumin IgG.
S B, Shurin, T P, Stossel
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The role of complement in C3 glomerulopathy
Molecular Immunology, 2015C3 glomerulopathy describes a spectrum of disorders with glomerular pathology associated with C3 cleavage product deposition and with defective complement action and regulation (Fakhouri et al., 2010; Sethi et al., 2012b). Kidney biopsies from these patients show glomerular accumulation or deposition of C3 cleavage fragments, but no or minor deposition
Peter F. Zipfel +11 more
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Platelet-associated complement C3 in thrombocytopenic states
British Journal of Haematology, 1983Platelet-associated complement components C3, C3d and C4 (PAC3, PAC3d, PAC4) were quantitated by a modification of the platelet radioactive anti-IgG test using highly purified C3 antibodies in 74 patients with immune thrombocytopenia (ITP), 26 patients with presumed nonimmune thrombocytopenia (NTP), and 114 normal individuals. Elevated PAC3 levels were
W, Kayser +3 more
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