Results 351 to 360 of about 1,025,521 (374)
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Complement C3 proteins in psoriasis
British Journal of Dermatology, 1989A new polymorphism of the complement factor C3 in human plasma was demonstrated by isotachophoresis in agarose gels followed by immunodetection with rabbit anti-human C3c and C3d immunoglobulins. Four bands were detected in the immunoprint of freshly drawn EDTA-plasma, which were C3s1, C3s2, C3f1 and C3f2. At least four additional C3 components in Mg2+
F Acevedo, Hans Hammar
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With complements:
SummaryC3 is a key complement protein, located at the nexus of all complement activation pathways. Extracellular, tissue, cell‐derived, and intracellular C3 plays critical roles in the immune response that is dysregulated in many diseases, making it an attractive therapeutic target.
Martin Kolev +4 more
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Complement C3 in Bernese Mountain dogs
Veterinary Clinical Pathology, 2010Background:Previous research suggests that low serum concentrations of the third component of complement (C3) are associated with both the susceptibility to infectious agents such asBorrelia burgdorferiand the development of glomerular disease. We hypothesized that low levels of C3 are associated with the coincident occurrence ofB. burgdorferiinfection
Gerber, Bernhard +4 more
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Inherited complement C3 deficiency: A defect in C3 secretion
European Journal of Immunology, 1994AbstractThe molecular basis of inherited complement C3 deficiency in a 20‐year‐old newly diagnosed male patient was studied. Using an enzyme‐linked immunosorbent assay, the patient's C3 serum level was found to be approximately 7 μg/ml, which is less than 1 % of normal.
Zvi Fishelson +4 more
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Definitions, 2020
Complement C3 is the central component of the human complement system. It is ~186 kDa in size, consisting of an α-chain (~110 kDa) and a β-chain (~75 kDa) that are connected by cysteine bridges. C3 in its native form is inactive. Cleavage of C3 into C3b (
A. Dinasarapu +3 more
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Complement C3 is the central component of the human complement system. It is ~186 kDa in size, consisting of an α-chain (~110 kDa) and a β-chain (~75 kDa) that are connected by cysteine bridges. C3 in its native form is inactive. Cleavage of C3 into C3b (
A. Dinasarapu +3 more
semanticscholar +1 more source
Treatment of C3 Glomerulopathy with Complement Blockers
Seminars in Thrombosis and Hemostasis, 2014C3 glomerulopathy (C3G) is a newly defined clinical entity comprising glomerular lesions with predominant C3 staining. Under this definition are now included membranoproliferative glomerulonephritis type II (dense deposit disease) and C3 glomerulonephritis.
Francesco Emma, Marina Vivarelli
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Complement C3 receptors: Structure and function
Molecular Immunology, 1984Significant progress has been made during the past few years toward elucidating the structure and function of various C3 receptors. Better understanding of the biochemical basis of the immune adherence phenomenon has been achieved. The availability of polyclonal and monoclonal antibodies to C3 receptors allowed more accurate studies of the cellular ...
M. Amin Arnaout, Harvey R. Colten
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Interaction of Fibronectin with Complement Component C3
Scandinavian Journal of Immunology, 1983The activation of the complement component C3 generates C3a and C3b fragments, and the physiological cleavage of C3b further yields C3c and C3d fragments. We studied here by enzyme immunoassay the ability of human plasma fibronectin to interact with native C3 of human sera and with isolated C3c and C3d fragments of C3.
A. Hautanen, Jorma Keski-Oja
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C3 and C6 Complement Types in Schizophrenia
Human Heredity, 1985C3 and C6 complement types were studied in schizophrenic patients and controls. The distributions of the three common C3 types (F, FS and S) among the patients was significantly different from that in the controls (p less than 0.005) and the frequency of the C3F gene was significantly increased (p less than 0.0005) among the patients.
C. Rudduck +3 more
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Complement C3 isoforms in Austrelaps superbus
Toxicon, 2008Complement C3 plays a pivotal role in both classical and alternate pathways. Lower organisms (urochordates and fishes) have multiple isoforms whereas higher organisms have a single C3 gene. In cobras, a closely related protein cobra venom factor (CVF) is expressed in their venom gland.
Syed Rehana, R. Manjunatha Kini
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