Purification of the human complement control protein C3b inactivator [PDF]
An alternative method of isolation from human plasma is described for C3b inactivator, C3bINA, the proteinase that in conjunction with either beta 1H or C4b-binding protein will hydrolyse respectively C3b or C4b, the activation products of the third, C3 and fourth, C4, components of complement. The purification is by chromatography of plasma on columns
L G, Crossley, R R, Porter
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Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution. [PDF]
The complement regulatory enzyme, C3b inactivator (C3bINA), has been purified from human serum by affinity chromatography on an anti-C3bINA Sepharose column. Subsequent chromatography on DEAE-cellulose and removal of IgG with anti-IgG Sepharose resulted in a product which was found to be homogeneous by polyacrylamide gel electrophoresis at pH 8.9 and ...
M K, Pangburn +2 more
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Diversity of Sites for Measles Virus Binding and for Inactivation of Complement C3b and C4b on Membrane Cofactor Protein CD46 [PDF]
The complement system membrane cofactor protein (MCP) CD46 serves as a C3b/C4b inactivating factor for the protection of host cells from autologous complement attack and as a receptor for measles virus (MV). MCP consists of four short consensus repeats (SCR) which are the predominant extracellular structural motif.
K, Iwata +8 more
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Purpose To investigate the use of ClinProt technique to identify cancer markers in plasma of patients suffering from squamous cell carcinoma of the penis (SCCP). Materials and Methods Plasma of 36 healthy subjects and 25 patients with
Paulo Ornellas +12 more
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Genetic variant in complement receptor 1 (CR1, CD35) is associated with a cluster of severe fatal COVID-19 in a family. [PDF]
Danial-Farran N +7 more
europepmc +1 more source
Subversion of the Complement System by Pseudomonas aeruginosa. [PDF]
Hastings CJ, Syed SS, Marques CNH.
europepmc +1 more source
Pseudomonas aeruginosa and the Complement System: A Review of the Evasion Strategies. [PDF]
González-Alsina A +3 more
europepmc +1 more source
Atypical haemolytic uremic syndrome with refractory multiorgan involvement and heterozygous CFHR1/CFHR3 gene deletion. [PDF]
Diep J, Potter D, Mai J, Hsu D.
europepmc +1 more source
CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome. [PDF]
Sugawara Y +7 more
europepmc +1 more source
Anti-factor H antibody and its role in atypical hemolytic uremic syndrome. [PDF]
Raina R +7 more
europepmc +1 more source

