Results 21 to 30 of about 3,381 (120)

Assembly of the cytolytic alternative pathway of complement from 11 isolated plasma proteins

open access: yesJournal of Experimental Medicine, 1978
The known cytolytic function of the alternative pathway in serum was quantitatively reproduced by combining 11 isolated plasma proteins at their respective serum concentrations.
Robert D. Schreiber   +1 more
semanticscholar   +1 more source

Functional properties of membrane-associated complement receptor CR1.

open access: yesJournal of Immunology, 1983
It was previously shown that membrane receptors for C3b (CR1) purified from human erythrocytes were powerful inhibitors of the complement cascade and that they encompass the regulatory functions of the serum proteins beta 1H (H) and C4-binding protein ...
K. Iida, V. Nussenzweig
semanticscholar   +1 more source

Lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibody

open access: yesJournal of Experimental Medicine, 1979
The dependence of antibody-and-complement-mediated lysis of virus- infected cells on the alternative pathway was examined utilizing the isolated cytolytic alternative pathway--a system consisting of the six purified proteins of the alternative pathway of
J. Sissons   +5 more
semanticscholar   +1 more source

Functional and antigenic properties of complement receptor type 2, CR2

open access: yesJournal of Experimental Medicine, 1987
This is the first report demonstrating that C3d receptor (CR2) has functional activity in regulating complement cascade. Purified CR2 was examined for its cofactor activity in factor I-mediated cleavage of membrane-bound iC3b. CR2 plus C3b inactivator (I)
K. Mitomo, T. Fujita, Kyoko Ida
semanticscholar   +1 more source

Solubilization of immune precipitates by six isolated alternative pathway proteins

open access: yesJournal of Experimental Medicine, 1981
Immune precipitates were solubilized by the alternative pathway of complement assembled from isolated proteins, i.e., C3, factor B, factor D, properdin, C3b inactivator (C3bINA), and beta 1H.
Fujita Teizo, Takata Yuko, Tamura Noboru
semanticscholar   +1 more source

Genetic variant in complement receptor 1 (CR1, CD35) is associated with a cluster of severe fatal COVID-19 in a family. [PDF]

open access: yesJ Infect, 2023
Danial-Farran N   +7 more
europepmc   +1 more source

Initiation of the alternative pathway of complement: recognition of activators by bound C3b and assembly of the entire pathway from six isolated proteins.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1978
R. Schreiber   +3 more
semanticscholar   +1 more source

Pseudomonas aeruginosa and the Complement System: A Review of the Evasion Strategies. [PDF]

open access: yesMicroorganisms, 2023
González-Alsina A   +3 more
europepmc   +1 more source

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