Results 101 to 110 of about 160,264 (281)

Complement System Deficiencies in Elite Athletes

Sports Medicine - Open
Background Although regular physical activity improves immune competency and reduces the prevalence of inflammatory diseases, strenuous training in elite athletes is associated with an increased susceptibility to infectious complications.
Libor Vítek, Jana Woronyczova, Veronika Hanzikova, Helena Posová   +3 more
doaj   +1 more source

Graph isomorphism completeness for trapezoid graphs

, 2015
The complexity of the graph isomorphism problem for trapezoid graphs has been open over a decade. This paper shows that the problem is GI-complete. More precisely, we show that the graph isomorphism problem is GI-complete for comparability graphs of ...
Takaoka, Asahi
core   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Purification of human complement subcomponent C4 [PDF]

FEBS Letters, 1979
Reboul, A., Thielens, N., Villiers, M.B., Colomb, M.G.   +3 more
openaire   +2 more sources

Comparative Oligo‐FISH Mapping Illuminates Chromosomal Evolution Among Rutaceae Species Diverged Over 50 Million Years

Advanced Science, EarlyView.
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He, Hainan Zhao, Xiaoxue Zeng, Zujun Yang, Wenting Li, Guoyan Zhang, Guangrong Li, Jian He, Bin Guan, Jiming Jiang   +9 more
wiley   +1 more source

Serum Complement C4 Levels Are a Useful Biomarker for Predicting End-Stage Renal Disease in Microscopic Polyangiitis. [PDF]

Int J Mol Sci, 2023
Matsuda S, Oe K, Kotani T, Okazaki A, Kiboshi T, Suzuka T, Wada Y, Shiba H, Hata K, Shoda T, Takeuchi T.   +10 more
europepmc   +1 more source

The complement system in renal homograft recipients [PDF]

, 1972
The whole serum complement and its components were studied in 24 recipients of 27 renal homografts. In 12 of 13 instances in which homograft rejection was diagnosed, it was accompanied by significant declines in CH50, IA50, C4, and C3 levels, and to a ...
Durst, AL, Groth, CG, Schroter, G, Starzl, TE, Torisu, M, Yokoyama, T   +5 more
core  

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Hypocomplementemia in Primary Sjogren’s Syndrome: A Retrospective Study of 120 Treatment-Naive Chinese Patients

International Journal of General Medicine, 2022
Meiju Zhou, Fang Yuan Department of Rheumatology and Immunology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of ChinaCorrespondence: Fang YuanDepartment of Rheumatology and ...
Zhou M, Yuan F
doaj