Advanced Synthesis &Catalysis, EarlyView.A ruthenium‐catalyzed azide–alkyne cycloaddition (RuAAC) reaction is reported for the synthesis of selenium‐substituted triazole products. Reaction regioselectivity is dependent on the identity of the non‐selenium substituent of the alkyne, which challenges the perceived understanding of RuAAC regioselectivity.
Frances E. Bugden +9 more
wiley +1 more source
Serum Complement C4 Levels Are a Useful Biomarker for Predicting End-Stage Renal Disease in Microscopic Polyangiitis. [PDF]
Int J Mol Sci, 2023 Matsuda S +10 more
europepmc +1 more source
Advanced Science, EarlyView.The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie +8 more
wiley +1 more source
Association between copy number variation of complement component
Journal of Biomedical Science, 2011 Background Gene copy number of complement component C4, which varies among individuals, may determine the intrinsic strength of the classical complement pathway.
Liao Wen-Ling +7 more
doaj +1 more source
Activation of Complement by Endotoxin: A Role for γ2 Globulin, C1, C4 and C2 in the Consumption of Terminal Complement Components by Endotoxin-Coated Erythrocytes [PDF]
, 1972 J. K. Phillips +2 more
openalex +1 more source
Membrane Receptors for IgG and Complement (C4, C3b and C3d) on Human Eosinophils and Neutrophils and Their Relation to Eosinophilia [PDF]
, 1977 Azlinda Anwar, A. B. Kay
openalex +1 more source
Advanced Science, EarlyView.A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu +12 more
wiley +1 more source
Anticomplementary activity of Fusobacterium polymorphum in normal and C4-deficient sources of guinea pig complement [PDF]
, 1977 Charles E. Hawley, William A. Falkler
openalex +1 more source
Advanced Science, EarlyView.Single‐molecule fluorescence microscopy is combined with proteomic profiling to fingerprint the morphology and composition of TDP‐43 protein aggregates found in post‐mortem motor neuron disease brain tissues. Aggregate fingerprints can distinguish disease from control donors and detect unexpected TDP‐43 pathology in SOD1‐MND.
Dezerae Cox +9 more
wiley +1 more source
Relevance of Complement C4 Deposits Localized to Distinct Vascular Compartments in ANCA-Associated Renal Vasculitis. [PDF]
Int J Mol Sci, 2022 Hakroush S +4 more
europepmc +1 more source