Background and Objectives: Deficiency in the complement system can lead to some autoimmune diseases, such as systemic lupus erythematosus. The purpose of this study was to investigate the levels of C3 and C4 complements in unstimulated saliva of ...
Bita Rohani+2 more
doaj
Enhancing Large-Scale AI Training Efficiency: The C4 Solution for Real-Time Anomaly Detection and Communication Optimization [PDF]
The emergence of Large Language Models (LLMs) has necessitated the adoption of distributed training techniques, involving the deployment of thousands of GPUs to train a single model. Unfortunately, the efficiency of large-scale distributed training systems is often suboptimal due to the increased likelihood of hardware errors in high-end GPU products ...
arxiv
Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects. [PDF]
Mansur F+7 more
europepmc +1 more source
Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. [PDF]
Lars Sottrup‐Jensen+9 more
openalex +1 more source
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to three years; all patients received mycophenolate mofetil and low‐dose ...
Brad H. Rovin+9 more
wiley +1 more source
Original Ultra-hard Orthorhombic Carbon allotropes C8 with lonsdaleite-type lon topology: Crystallographic and DFT investigations [PDF]
The lon topology inherent to lonsdaleite C4 hexagonal diamond is shown to characterize three original carbon allotropes C8 in the orthorhombic system with irregular orientations of the C4 tetrahedra. The octacarbon stoichiometries were devised from crystal structure engineering and identified close to lonsdaleite from density functional theory (DFT ...
arxiv
Structure-Based Modeling of Complement C4 Mediated Neutralization of Adenovirus. [PDF]
Emerson CC, Stewart PL.
europepmc +1 more source
Objective The presence of anti‐nuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti‐dsDNA is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA serum levels are associated ...
Hugo J. van Dooren+16 more
wiley +1 more source
On graphs without four-vertex induced subgraphs [PDF]
Given a family F of graphs, a graph G is F-free if it does not contain any graph in F as an induced subgraph. The problem of determining the complexity of colouring (claw, 4K1)- free graphs is a well-known open problem. In this paper we solve the colouring problem for a subclass of (claw, 4K1)-free graphs.
arxiv
Conformational changes in complement component C4 induced by activation, treatment with amines, chaotropes, or freezing-thawing, detectable by radioiodination using lactoperoxidase. [PDF]
I. von Zabern, Irma Gigli
openalex +1 more source