A Study of Serum C3 and C4 Levels in Burn Patients: Possible Prognostic Markers?
JK Science, 2021 Background: Burns are a public health problem across the world and a major burden on health care resources. Identifying major burns including those more likely to develop sepsis will help a lot in their management. Purpose: This study was undertaken to
Sanjay Sadhu, Kiran Bhat
doaj
Conformational changes in complement component C4 induced by activation, treatment with amines, chaotropes, or freezing-thawing, detectable by radioiodination using lactoperoxidase. [PDF]
, 1982 I. von Zabern, Irma Gigli
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Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica
Advanced Science, EarlyView.The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon +8 more
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Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q. [PDF]
, 1988 C Bindon +3 more
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Regulation of B-cell tolerance by complement C4
Arthritis Research & Therapy, 2004 Systemic lupus erythematosus (SLE) is a B-cell-dependent autoimmune disease characterized by autoantibodies specific for nuclear antigens such as dsDNA and histones. Apoptotic blebs released from dying cells are thought to represent a major source of autoantigen.
Marat Alimzhanov +2 more
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Advanced Science, EarlyView.This study primarily reveals that PM2.5‐derived Fe‐containing particles, particularly magnetite, are specifically enriched in the heart. Here, they interact with NCOA4 in endothelial cells, disrupt iron homeostasis by enhancing ferritinophagy, and subsequently trigger the process of EndMT through the NCOA4/KLF5 pathway.
Qinglin Sun +11 more
wiley +1 more source
C-Reactive Protein Levels Are Associated with Complement C4 Deposits and Interstitial Arteritis in ANCA-Associated Renal Vasculitis. [PDF]
Int J Mol Sci, 2023 Korsten P, Baier E, Hakroush S, Tampe B.
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Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4. [PDF]
, 1985 Lars Sottrup‐Jensen +9 more
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Advanced Science, EarlyView.An electro–magnetic–porous multigradient nanofibrous electromagnetic interference (EMI) membrane is fabricated via shear‐induced in situ fibrillation and layer‐by‐layer assembly. Leveraging a multigradient‐induced “impedance matching–polarization–reabsorption” synergistic mechanism, the membrane achieves absorption‐dominated high‐efficiency EMI ...
Runze Shao +5 more
wiley +1 more source
Postinjury complement C4 activation is associated with adverse outcomes and is potentially influenced by plasma resuscitation. [PDF]
J Trauma Acute Care Surg, 2022 Schaid TR +14 more
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