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Urgent diagnosis of hereditary angioedema in the ICU and ED: the critical role of rapid complement testing - a case report. [PDF]
Dungan LS, Khalib K, Curley D, Keogan M.
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Functional Diversity of Complement C4 Isotypes in Bony Fish Complement
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Complement Factor C4 in Schizophrenia
Human Heredity, 1985The complement factor C4 was studied in 165 schizophrenic patients and in 330 controls. A highly significant increase in the frequency of C4B deficiency (BQO) was found among the schizophrenic patients compared with controls (p less than 0.0005).
C, Rudduck +4 more
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Polymorphism of human complement component C4
Immunogenetics, 1985An assessment has been made of the polymorphism of human complement component C4 by comparing derived amino acid sequences of cDNA and genomic DNA with limited amino acid sequences. In all, one complete and six partial sequences have been obtained from material from three individuals and include two C4A and two C4B alleles.
K T, Belt +3 more
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C4 complement allotypes in juvenile dermatomyositis
Human Immunology, 1988Twenty probands with juvenile dermatomyositis and their relatives were studied to determine the inherited segregation patterns of class I, II, and III HLA region markers including C4A, C4B, Bf, and C2 complement polymorphisms. The extended haplotype B8, DR3, C4A*Q0, C4B*1, C2*C, and Bf*S was present in 13 of the 20 probands.
S A, Robb +7 more
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Genetic studies of complement C4 in man
Human Genetics, 1979A C4 variant found in about 5% of the population is described. The fast-moving part of this variant is governed by an allele (Fx) codominant to F. The Fx allele is in very strong linkage disequilibrium with HLA-B17 as the linkage disequilibrium parameter accounted for nearly 100% of the haplotype frequency of B17,Fx.
G B, Petersen +3 more
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Complement components (C3, C4) in childhood asthma
The Indian Journal of Pediatrics, 2005To assess the involvement of complements (C3, C4) in the pathophysiology of bronchial asthma.Selection of patients (n = 64) were made according to the recommended international criteria for diagnosis and classification of asthma. Serum levels of complement components (C3, C4) were measured by radial immunodiffusion technique in 64 Libyan children (age:
F I E, Najam +2 more
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Genetics of complement C4. Two homoduplication haplotypes C4S C4S and C4F C4F in a family
Human Genetics, 1982A family in which two homoduplicated C4 haplotypes (or supergenes) segregate is described. One haplotype C4F*3 C4F*2.2 is composed of two C4F alleles and the other C4S*5.1 C4S*1 of two C4S alleles. The C4F duplication haplotype is a partial inhibitor of the Rodgers antigen, and judged from our family and population material, it seems to be rather ...
G, Bruun-Petersen +3 more
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