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Reference Typing Report for Complement Component C4
Experimental and Clinical Immunogenetics, 1998During the 7th Complement Genetics Workshop, Mainz, Germany, May 1998, a complement component C4 typing exercise took place with the aim of applying present technologies to the definition of <i>reference C4 alleles/phenotypes</i> and the recognition of nonexpressed (Q0) C4 alleles within expressed haplotypes.
G, Mauff +6 more
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Complement components (C3, C4) in childhood asthma
The Indian Journal of Pediatrics, 2005To assess the involvement of complements (C3, C4) in the pathophysiology of bronchial asthma.Selection of patients (n = 64) were made according to the recommended international criteria for diagnosis and classification of asthma. Serum levels of complement components (C3, C4) were measured by radial immunodiffusion technique in 64 Libyan children (age:
F I E, Najam +2 more
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Interaction of nucleophilic compounds with complement component C4
Comparative Immunology, Microbiology and Infectious Diseases, 1988Drugs which induce systemic lupus erythematosus as a toxic side effect have been shown to inhibit the covalent binding of C4, which is an important event in immune complex clearance in normal individuals. Human C4 is encoded at two polymorphic loci, C4A and C4B within the Major Histocompatibility Complex and patients with idiopathic SLE are more likely
E, Sim, M, Wood, K E, Parker, A, Jones
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Isolation of the Fourth Component (C4) of Rat Complement
The Journal of Immunology, 1979Abstract The fourth component of rat complement was purified to homogeneity by sequential chromatography of rat plasma in benzamidine on QAE-A50, SP-C50, hydroxyapatite, and gel filtration on Bio-Gel A 1.5. The final material was homogeneous on SDS-PAGE analysis and had a calculated m.w. of 198,000. A monospecific antibody against rat C4
M R, Daha, L A, van ES
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The complement component C4 in sudden infant death
European Journal of Pediatrics, 1999The aim of the present study was to compare partial deletions of the complement C4 gene in victims of totally unexplained sudden infant death (SID) (n = 89) and borderline SID (n = 15) with and without slight infections prior to death, in cases of infectious death (n = 19), and in living infants with and without infections (n = 84).
S H, Opdal +3 more
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Family studies of complement C4 and HLA in man
Human Genetics, 1981At least 12 different C4 gene products with a three band pattern have been identified after electrophoresis of sera pretreated with neuraminidase. Segregation analysis showed at least 12 different C4 haplotypes (or supergenes), of which five represent a single gene product and seven are duplications each composed of an F and an S gene.
G, Bruun-Petersen +4 more
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Post-transcriptional regulation of complement C4 in low C4-producing strain of mouse
Immunogenetics, 1990The expression of the fourth component of complement (C4) of the mouse can differ 20-fold and is determined by C4-high (C4h) or C4-low (C4l) alleles. To investigate the molecular mechanisms underlying the differences in C4 expression, we compared the transcriptional activity of the C4 genes between high and low C4-producer strains of mice (B10 and FM ...
K, Nakayama +5 more
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Detection of complement C4 with a piezoelectric immunosensor
Chinese Journal of Chemistry, 1998AbstractA piezoelectric immunosensor has been developed for the detection of complement C4. Anti‐C4 antibody was immobilized onto the gold electrodes of a 9 MHz AT‐cut piezoelectric crystal. The coated crystal with the physical adsorption method to immobilize antibody showed the better results than the polyethyleneimine adhesion, glutaraldehyde cross ...
Hu Ji‐Ming +3 more
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Clinical Immunology and Immunopathology, 1985
Serum C4 concentrations and C4 allotypes were determined wherever possible on eight dogs with an autoimmune disorder characterized by antinuclear antibody (ANA) positivity, pyrexia, and seronegative arthritis. Three of the six dogs tested serially showed hypocomplementemia at disease onset with return to normal concentrations with clinical remission ...
Day, M.J. +5 more
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Serum C4 concentrations and C4 allotypes were determined wherever possible on eight dogs with an autoimmune disorder characterized by antinuclear antibody (ANA) positivity, pyrexia, and seronegative arthritis. Three of the six dogs tested serially showed hypocomplementemia at disease onset with return to normal concentrations with clinical remission ...
Day, M.J. +5 more
openaire +2 more sources

