Results 231 to 240 of about 160,264 (281)

C4 complement allotypes in juvenile dermatomyositis

Human Immunology, 1988
Twenty probands with juvenile dermatomyositis and their relatives were studied to determine the inherited segregation patterns of class I, II, and III HLA region markers including C4A, C4B, Bf, and C2 complement polymorphisms. The extended haplotype B8, DR3, C4A*Q0, C4B*1, C2*C, and Bf*S was present in 13 of the 20 probands.
S A, Robb, A H, Fielder, C E, Saunders, N J, Davey, M W, Burley, D H, Lord, J R, Batchelor, V, Dubowitz   +7 more
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Genetic studies of complement C4 in man

Human Genetics, 1979
A C4 variant found in about 5% of the population is described. The fast-moving part of this variant is governed by an allele (Fx) codominant to F. The Fx allele is in very strong linkage disequilibrium with HLA-B17 as the linkage disequilibrium parameter accounted for nearly 100% of the haplotype frequency of B17,Fx.
G B, Petersen, I J, Sørensen, L, Buskjaer, L U, Lamm   +3 more
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Complement components (C3, C4) in childhood asthma

The Indian Journal of Pediatrics, 2005
To assess the involvement of complements (C3, C4) in the pathophysiology of bronchial asthma.Selection of patients (n = 64) were made according to the recommended international criteria for diagnosis and classification of asthma. Serum levels of complement components (C3, C4) were measured by radial immunodiffusion technique in 64 Libyan children (age:
F I E, Najam, A S M, Giasuddin, A H, Shembesh   +2 more
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Genetics of complement C4. Two homoduplication haplotypes C4S C4S and C4F C4F in a family

Human Genetics, 1982
A family in which two homoduplicated C4 haplotypes (or supergenes) segregate is described. One haplotype C4F*3 C4F*2.2 is composed of two C4F alleles and the other C4S*5.1 C4S*1 of two C4S alleles. The C4F duplication haplotype is a partial inhibitor of the Rodgers antigen, and judged from our family and population material, it seems to be rather ...
G, Bruun-Petersen, L U, Lamm, B K, Jacobsen, T, Kristensen   +3 more
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Sex, MHC and complement C4 in autoimmune diseases

Trends in Immunology, 2004
Autoimmune diseases are estimated to affect 10-50 million people in the United States, and untold millions worldwide. Nearly 80% of all people with autoimmune diseases are women, and a strong association of these diseases with MHC genes has been known for some time. However, very little is known about what causes autoimmune diseases or the factors that
C Yung, Yu, Caroline C, Whitacre
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C4A7: A New Variant of Human Complement C4

Human Heredity, 1988
A rare variant of complement C4 was found in 2 related individuals. It has the most anodic mobility found to date, no hemolytic activity detected by the overlay technique and a Bgl II RFLP pattern very similar to that of the C4A6 type.
M, Abbal, F, de Paoli, M, Cuccia-Belvedere, M, Martinetti   +3 more
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Genetic polymorphism of complement C4 in the dog

Tissue Antigens, 1984
Plasma samples from 129 dogs have been typed using an immunofixation technique to define the polymorphism of canine C4. The mode of inheritance was inferred by study of four large pedigrees. In contrast to the situation in man, canine C4 may be encoded by a single locus. At least five different co‐dominant structural alleles have been detected.
P H, Kay, R L, Dawkins
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The complement component C4 in sudden infant death

European Journal of Pediatrics, 1999
The aim of the present study was to compare partial deletions of the complement C4 gene in victims of totally unexplained sudden infant death (SID) (n = 89) and borderline SID (n = 15) with and without slight infections prior to death, in cases of infectious death (n = 19), and in living infants with and without infections (n = 84).
S H, Opdal, A, Vege, A K, Stave, T O, Rognum   +3 more
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Interaction of nucleophilic compounds with complement component C4

Comparative Immunology, Microbiology and Infectious Diseases, 1988
Drugs which induce systemic lupus erythematosus as a toxic side effect have been shown to inhibit the covalent binding of C4, which is an important event in immune complex clearance in normal individuals. Human C4 is encoded at two polymorphic loci, C4A and C4B within the Major Histocompatibility Complex and patients with idiopathic SLE are more likely
E, Sim, M, Wood, K E, Parker, A, Jones
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Complement C4 Phenotypes in Dementia of the Alzheimer Type

Human Heredity, 1988
Complement C4 phenotype distribution was studied in 64 patients with dementia of the Alzheimer type. In contrast to reported findings we failed to find a significant association between C4B2 gene frequency and Alzheimer's dementia.
Eikelenboom, P., Goetz, J., Pronk, J. C., Hauptmann, G.   +3 more
openaire   +3 more sources