Results 111 to 120 of about 675,301 (233)
O envolvimento dos alótipos de C4 na patogênese das doenças humanas [PDF]
, 2004 The complement system is an important humoral defense mechanism that plays a relevant role against microbial agents, inflammatory response control, and immunocomplex clearance. Classical complement pathway activation is antibody-dependent.
Gorescu, Rosa G. +4 more
core +3 more sources
Association Study of the Complement Component C4 Gene in Tardive Dyskinesia
Frontiers in Pharmacology, 2019 Tardive dyskinesia (TD) is a movement disorder that may develop in schizophrenia patients being treated long-term with antipsychotic medication. TD interferes with voluntary movements and leads to stigma, and can be associated with treatment non ...
Clement C. Zai +30 more
doaj +1 more source
Immunometabolism of Liver Xenotransplantation and Prospective Solutions
Advanced Science, Volume 12, Issue 9, March 6, 2025.After xenotransplantation, pig livers will replace those of human patients to maintain the stability of metabolism and immune system. The incompatibility of immunometabolism between humans and pigs induces rejection, inflammation, coagulation dysfunction, and liver failure. The profile of immunometabolism pre‐transplantation and post‐transplantation is
Shoulong Deng +4 more
wiley +1 more source
Complement Activation Is Associated With Disease Severity in Multiple Sclerosis. [PDF]
BACKGROUND AND OBJECTIVES Histopathologic studies have identified immunoglobulin (Ig) deposition and complement activation as contributors of CNS tissue damage in multiple sclerosis (MS).
Achtnichts, Lutz +29 more
core +1 more source
Complement system in dermatological diseases – fire under the skin
Frontiers in Medicine, 2015 The complement system plays a key role in several dermatological diseases. Overactivation, deficiency or abnormality of the control proteins are often related to a skin disease.
Jaana Helena Panelius +4 more
doaj +1 more source
Advanced Science, Volume 12, Issue 12, March 27, 2025.Innate immune activation plays a vital role in the development of Alzheimer's disease, yet the mechanisms remain unclear. This study identifies microglial cGAMP synthase (cGAS) as a central driver of amyloid‐β pathology and unveils a novel microglia‐myelin crosstalk mediated by pleiotrophin. These findings provide groundbreaking insights into microglia'
Sijia He +8 more
wiley +1 more source
Metabolites, 2019 Gestational trophoblastic disease (GTD) is a group of highly aggressive, rare tumors. Human chorionic gonadotropin is a common biomarker used in the diagnosis and monitoring of GTD.
Paulina Banach +6 more
doaj +1 more source
Complement‐mediated adherence of immune complexes to human erythrocytes
FEBS Letters, 1987 The classical pathway of complement is required for the adherence of soluble tetanus toxoid (TT)‐human anti‐TT complexes to erythrocytes. Using human C4‐deficient serum we compared the capacity of the two forms of human C4 (C4A and C4B) to mediate this function: C4A was shown to be 1.5‐fold more efficient than C4B.
Jean-Pierre Paccaud +2 more
openaire +3 more sources
VLBI and Single Dish Monitoring of 3C84 in the Period of 2009-2011
, 2012 The radio galaxy 3C 84 is a representative of gamma-ray-bright misaligned active galactic nuclei (AGNs) and one of the best laboratories to study the radio properties of the sub-pc jet in connection with the gamma-ray emission.
A. Doi +35 more
core +1 more source