Factor H gene variants in Japanese: Its relation to atypical hemolytic uremic syndrome [PDF]
, 2011 Mutations and polymorphisms of factor H gene (FH1) are known to be closely involved in the developmentof atypical hemolytic uremic syndrome (aHUS). Several groups have identified disease risk mutations andpolymorphisms of FH1 for the development of aHUS,
Fujihara Noriko +10 more
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Deficiency of Human Complement Protein C4 Due to Identical Frameshift Mutations in the C4A and C4B Genes [PDF]
, 1999 Marja‐Liisa Lokki +5 more
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Complement proteins changes in ischemic stroke patients and their relation to outcome
ImmunobiologyWe studied plasma levels of complement system factors C1q, C2, C3, C3b, C4, C4b, C5, C5a, C9 of 84 patients with ischemic stroke within 24 h from onset of symptoms and on seventh day after admission, using Luminex immunoassay.
Radosław Opiła +5 more
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Molecular cloning and characterization of the cDNA coding for C4b-binding protein, a regulatory protein of the classical pathway of the human complement system [PDF]
, 1985 Lap-Ping Chung +2 more
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Structural analysis of human complement protein H: homology with C4b binding protein, beta 2-glycoprotein I, and the Ba fragment of B2. [PDF]
, 1986 Torsten Nygaard Kristensen +2 more
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Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1 [PDF]
, 2017 Objectives Membrane-targeted application of complement inhibitors may ameliorate ischemia/reperfusion (I/R) injury by directly targeting damaged cells. We investigated whether Mirococept, a membrane-targeted, myristoylated peptidyl construct derived from
Banz, Yara +9 more
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The fourth component of human complement treated with amines or chaotropes or frozen-thawed (C4b-like C4): interaction with C4 binding protein and cleavage by C3b/C4b inactivator. [PDF]
, 1982 I. von Zabern +3 more
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Protein C Replacement in Severe Meningococcemia: Rationale and Clinical Experience [PDF]
, 2017 Severe meningococcemia, which is associated with hemodynamic instability, purpura fulminans and disseminated intravascular coagulation, still has a high mortality rate, and patients who survive are often left invalids because of amputations and organ ...
Alberio, Lorenzo +2 more
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C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation [PDF]
, 2005 Leendert A. Trouw +4 more
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