Results 191 to 200 of about 424,323 (243)

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

iMetaMed, EarlyView.
A pan‐cancer atlas deciphers tumor‐induced reprogramming in bone metastases. Malignant evolution toward MYC/proliferation is a hallmark of bone metastases. Niche‐mediated immune dysfunction is characterized by immature pDCs, impaired antigen presentation and phagocytosis in TAMs, and exhausted T cells.
Yitong Pan, Zhou Yang, Junyuan Deng, Feng Liu, Guang Lei   +4 more
wiley   +1 more source

Small Area Consumption Estimates Combining Survey and Financial Footprints Data

Journal of Applied Econometrics, EarlyView.
ABSTRACT We estimate average equivalised consumption measures across 370 local authority districts in Great Britain, using small‐area estimation methods that combine information from a household budget survey, a much larger survey of local demographics and employment, and area‐level information on bank account outflows and energy consumption.
Peter Levell, Lars Nesheim, Gautam Vyas
wiley   +1 more source

Rethinking ethanol separation in continuous spirit production from a process intensification perspective

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Continuous neutral‐alcohol and food‐grade ethanol production is an energy‐intensive process in which distillation and rectification alone account for 50–85% of total plant energy use. While significant advances in separation technology have emerged over the past two decades, the spirits industry continues to rely predominantly on multi‐effect ...
Anton A Kiss
wiley   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

On Fork‐Free t‐Perfect Graphs

Journal of Graph Theory, EarlyView.
ABSTRACT In an effort to understand the complexity of the maximum independent set problem, Chvátal introduced t‐perfect graphs. While a full characterization of this class remains open, important progress has been made for claw‐free graphs [Bruhn and Stein, Math. Program. 2012] and P 5 ${P}_{5}$‐free graphs [Bruhn and Fuchs, SIAM J. Discrete Math. 2017]
Yixin Cao, Shenghua Wang
wiley   +1 more source

Integrating Knowledge Management Into ERP Selection: A Fuzzy Multi‐Criteria Decision‐Making Model Based on Gray Theory in the Automotive Industry

Knowledge and Process Management, EarlyView.
ABSTRACT Enterprise Resource Planning (ERP) systems are integrated business management tools used by organizations to manage data and processes across various functions. While financial and technical considerations remain central to ERP selection, sustainable success also depends on the system's ability to support Knowledge Management (KM).
Deniz Sadat Sebti Esmail Pour, Ali Faghfouri   +1 more
wiley   +1 more source

From Numbers to Choice: How Numerical Sustainability Claims Shape Visual Attention and Purchase Decisions in Fashion

Psychology &Marketing, EarlyView.
ABSTRACT Sustainability information is difficult for consumers to evaluate because environmental performance represents a credence attribute. Although numerical sustainability claims have been shown to improve consumers' perceptions of sustainability communication, little is known about whether they influence product choice under realistic marketplace ...
Elena Gasulla Tortajada, Paulo Duarte, Susana C. Silva, Enrique Bigné   +3 more
wiley   +1 more source

Why Use Immersive Virtual Reality to Assess Gait in Functional Motor Disorders?

Movement Disorders, EarlyView.
Abstract Background Functional motor disorders (FMD) are disabling conditions modulated by attentional demands. Immersive virtual reality (iVR) engages multiple attentional and sensory networks, but its application in people with FMD (PwFMD) remains limited.
Marialuisa Gandolfi, Chiara Bonetto, Corrado Perin, Angela Sandri, Giulia Bonardi, Ilaria Antonella Di Vico, Laura Avanzino, Elisa Pelosin, Mauro Crestani, Christian Geroin, Denis Vidale, Marco Pirini, Mirta Fiorio, Michele Tinazzi, Francesca Salaorni   +14 more
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source