Results 221 to 230 of about 1,060,485 (284)

An Enzymatic Platform for Late‐Stage (Radio)isotope Labelling of Oligonucleotides With Methyltransferases

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson, Ulrich Kauhl, Martin R. Edelmann, Florian P. Seebeck   +3 more
wiley   +2 more sources

Complement mediated thrombotic microangiopathy after liver transplantation in combination with a novel C6 variant of uncertain significance. [PDF]

Front Immunol
Pollmann NS, Hauptmann L, Busch M, Pollmann L, Tannapfel A, Rohland O, Ali Deeb A, Rauchfuß F, Settmacher U, Dondorf F.   +9 more
europepmc   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring. [PDF]

Ann Clin Transl Neurol
Saccà F, Pelto R.
europepmc   +1 more source

Resource Recovery From Food Processing Wastewater Through Microalgae‐Driven Carbon Chain Rearrangement

GCB Bioenergy, Volume 18, Issue 10, October 2026.
Carbon chain rearrangement reframes food‐processing wastewater treatment from COD removal to controlled carbon recovery. By coupling microalgal biosynthesis with bacterial substrate transformation, algal–bacterial consortia can redirect heterogeneous wastewater carbon toward recoverable biomolecules.
Guanghong Luo, Shoukai Guo, Yu Xie, Liqin Sun, Ashiwin Vadiveloo, Zhongliang Sun   +5 more
wiley   +1 more source

FcRn antagonist and C5 complement inhibitor as early rescue strategies in severe Myasthenia Gravis: a two-case report. [PDF]

Front Immunol
Parisi M, Molitierno N, Alberti C, Gagliardi D, Velardo D, Comi GP, Corti SP.   +6 more
europepmc   +1 more source

Integrated Transcriptomic and Proteomic Analysis Elucidates the Mechanisms of Huperzine A Injection Against Cerebral Ischemia/Reperfusion Injury. [PDF]

Drug Des Devel Ther
Wang Y, Xie L, Gao Y.
europepmc   +1 more source

Real-World Treatment Adherence and Persistence with C5 Inhibitor Therapy Versus Satralizumab in Patients with Neuromyelitis Optica Spectrum Disorder in Japan. [PDF]

Neurol Ther
Chihara N, Lee J, Yu JC, Numajiri N, Misu T.   +4 more
europepmc   +1 more source

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

PNH extravascular hemolysis: exploring clinical significance. [PDF]

Blood Adv
Notaro R, Risitano AM.
europepmc   +1 more source