Results 201 to 210 of about 1,060,485 (284)

Pegcetacoplan as a targeted C3 inhibitor in C3 glomerulopathy and immune-complex MPGN. [PDF]

Ann Med Surg (Lond)
Habib E, Hajj F.
europepmc   +1 more source

Modern Slavery in Supply Chains: A Framing Perspective on Managerial Responses to Transparency Legislation

Journal of Supply Chain Management, EarlyView.
ABSTRACT Innovative legislation aspires for an extra‐jurisdictional effect on modern slavery in supply chains through increased transparency. Evidence to date suggests that firms are not rising to this challenge, and, if anything, mandatory reporting practices are coalescing around superficial reports decoupled from policy objectives. To decide how the
Bruce Pinnington, Alexandra Williams‐Woods   +1 more
wiley   +1 more source

Complement C5 inhibition in generalized myasthenia gravis is associated with improved survival and increased cardiovascular risk. [PDF]

Front Immunol
Vahldieck C, Fels B.
europepmc   +1 more source

A Genetically Encoded Marker for Imaging of Internal Plasmodium Membranes

Molecular Microbiology, EarlyView.
IMMP is a peptide‐based marker that labels internal membranes across multiple stages and species of the malaria‐causing parasite Plasmodium. It works in both live and fixed samples and supports long‐term live‐cell imaging. ABSTRACT Fluorescence microscopy is a powerful tool to analyze the subcellular architecture, and long‐term live‐cell imaging ...
Leah Zink, Viola Reuschenbach, Samy Sid Ahmed, Muriel Lauer, Jana Niethammer, Aistė Kudulytė, Katharina Zorko, Oliver T. Fackler, Franziska Hentzschel, Markus Ganter   +9 more
wiley   +1 more source

Complement C5 inhibitors as add-on rescue treatment in severe AQP4-antibody neuromyelitis optica spectrum disorder attacks: a case series and literature review. [PDF]

Ther Adv Neurol Disord
Gan KX, Abu Hassan SHB, Tan XL, Li KZ, Thirugnanam U, Yeo T.   +5 more
europepmc   +1 more source

Plasmatic Profiling of Individuals With Combinations of Type 2 Diabetes Mellitus, Dyslipidemia and Periodontitis: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira, Sâmia Cruz Tfaile Corbi, Alliny de Souza Bastos, Silvana Regina Perez Orrico, Cristiane Ribeiro Salmon, Yizhi Xiao, Walter Luiz Siqueira, Raquel Mantuaneli Scarel‐Caminaga   +7 more
wiley   +1 more source

Clinical Course After a Single Cycle of Rozanolixizumab in Generalized Late-Onset Myasthenia Gravis. [PDF]

J Clin Neurol
Aritake S, Nagai A.
europepmc   +1 more source

Saturating mutagenesis on the Ser118 residue responsible for the spectral tuning mechanism of the orange/green‐reversible cyanobacteriochrome AM1_1499g1

Plant Biology, EarlyView.
This graphical abstract illustrates our systematic site‐saturation mutagenesis at the Ser118 position of the AM1_1499g1 GAF domain. By replacing this single residue, we generated a diverse array of variants with distinct spectral properties, demonstrating the remarkable molecular plasticity of cyanobacteriochromes and their customizability for ...
A. Yoneda, T. Suzuki, R. Narikawa
wiley   +1 more source

Shifting From Systemic to Precision-Targeted Complement Therapies: Opportunities and Hurdles. [PDF]

Eur J Immunol
Mannes M, Zelek WM, Trouw LA.
europepmc   +1 more source

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

Transfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman, Meghana Vivek, Rida Hasan, Siobán Keel, Laura Connelly‐Smith   +4 more
wiley   +1 more source