Results 71 to 80 of about 80,611 (190)
Proteomic analysis of skin invasion by blood fluke larvae. [PDF]
, 2008 BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon +7 more
core +1 more source
Complement factor H in host defense and immune evasion [PDF]
Cellular and Molecular Life Sciences, 2016 Complement is the major humoral component of the innate immune system. It recognizes pathogen- and damage-associated molecular patterns, and initiates the immune response in coordination with innate and adaptive immunity. When activated, the complement system unleashes powerful cytotoxic and inflammatory mechanisms, and thus its tight control is ...
R. Parente +3 more
openaire +3 more sources
Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M
Nature Communications, 2023 Plasmodium falciparum causes the most severe malaria in humans. Immunoglobulin M (IgM) serves as the first line of humoral defense against infection and potently activates the complement pathway to facilitate P. falciparum clearance.
Chenggong Ji +6 more
doaj +1 more source
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity [PDF]
, 2013 Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Benfield, C T O +6 more
core +1 more source
Staphylococcal Proteases Aid in Evasion of the Human Complement System [PDF]
Journal of Innate Immunity, 2013 <i>Staphylococcus aureus</i> is an opportunistic pathogen that presents severe health care concerns due to the prevalence of multiple antibiotic-resistant strains. New treatment strategies are urgently needed, which requires an understanding of disease causation mechanisms.
Jusko, Monika +9 more
openaire +6 more sources
PLoS Pathogens, 2017 Whooping cough, or pertussis, is a contagious disease of the respiratory tract that is re-emerging worldwide despite high vaccination coverage. The causative agent of this disease is the Gram-negative Bordetella pertussis. Knowledge on complement evasion
Elise S Hovingh +5 more
doaj +1 more source
Molecular mechanisms of complement evasion: learning from staphylococci and meningococci [PDF]
Nature Reviews Microbiology, 2010 The complement system is a crucial component of the innate immune response in humans. Recent studies in Staphylococcus aureus and Neisseria meningitidis have revealed how these bacteria escape complement-mediated killing. In addition, new structural data have provided detailed insights into the molecular mechanisms of host defence mediated by the ...
Serruto, D. +4 more
openaire +4 more sources
Technology and Biological Weapons: Future Threats [PDF]
, 2004 Ye
Davison, N., Millett, P., Nixdorff, K.
core
Visibility Graphs, Dismantlability, and the Cops and Robbers Game [PDF]
, 2016 We study versions of cop and robber pursuit-evasion games on the visibility graphs of polygons, and inside polygons with straight and curved sides. Each player has full information about the other player's location, players take turns, and the robber is ...
Lubiw, Anna +2 more
core +3 more sources
How Does Complement Affect Hematological Malignancies: From Basic Mechanisms to Clinical Application
Frontiers in Immunology, 2020 Complement, as a central immune surveillance system, can be activated within seconds upon stimulation, thereby displaying multiple immune effector functions.
Shanshan Luo +7 more
doaj +1 more source