Results 71 to 80 of about 505,979 (246)
PLoS PathogensBorreliella burgdorferi, the causative agent of Lyme disease, has evolved unique complement evasion proteins that promote its ability to establish and maintain infection in mammalian hosts. Among these is B.
Alexandra D Powell-Pierce +6 more
doaj +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Virus complement evasion strategies
, 2003 The immune system has a variety of tools at its disposal to combat virus infections. These can be subdivided roughly into two categories: 'first line defence', consisting of the non-specific, innate immune system, and 'adaptive immune response', acquired
Herman W. Favoreel +7 more
core +1 more source
Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy
Advanced Materials, EarlyView.MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo +9 more
wiley +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Advanced Materials, EarlyView.Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Advanced Materials Technologies, EarlyView.Dense tactile streams from across the humanoid body converge on collide in a central wiring and data bottleneck. By relocating computation closer to and then into the skin itself, near‐ and in‐sensor architectures, together with neuromorphic computing, chart a path toward perception‐native electronic skin, in which the conversion of stimulus into ...
Mijin Kim +6 more
wiley +1 more source
Novel evasion mechanisms of the classical complement pathway
, 2016 Complement is a network of soluble and cell surfaceassociated proteins that gives rise to a self-amplifying, yet tightly regulated system with fundamental roles in immune surveillance and clearance.
Zwarthoff, Seline A. +5 more
core
Advanced Robotics Research, EarlyView.An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy +13 more
wiley +1 more source
Standard models of tax evasion implicitly assume that evasion is either fully detected, or not detected at all. Empirically, this is not the case, casting into doubt the traditional rationales for interior evasion choices.
Dirk Niepelt
core
The impact of complement evasion on transmission of malaria
, 2022 S.243As part of the innate immune system, human complement is a first line of defence against microbial invaders. However, microbes can evade complement recognition by binding to regulator proteins that normally protect host cells from complement ...
Lasonder, E. +7 more
core +1 more source