CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
Systemic complement factors in aging, Alzheimer's disease and other dementias: a longitudinal study over 10 years. [PDF]
Fu X +19 more
europepmc +1 more source
Comprehensive analysis of complement activation in a hydroxyurea-treated patient cohort with sickle cell disease. [PDF]
Diatlov D +3 more
europepmc +1 more source
A young woman with membranoproliferative glomerulonephritis and persistent hypocomplementemia: a case report. [PDF]
Li H +5 more
europepmc +1 more source
Primary membranoproliferative glomerulonephritis: natural history, pathogenesis, and treatment. [PDF]
Filippone EJ, Farber JL.
europepmc +1 more source
The ability of relapsing fever <i>Borrelia</i> species to survive in chicken serum <i>in vitro</i> and its correlation to interaction with serum components reactive to a polyclonal anti-complement regulator factor H antibody. [PDF]
Jakobsson T, Bergström S, Normark J.
europepmc +1 more source
Oxygen-dependent modulation of the human complement system during acute normobaric hypoxia: a translational plasma proteomics study. [PDF]
Lang A +16 more
europepmc +1 more source
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Biochemical and Biophysical Research Communications, 2021Serine proteases are fundamental components of biology, including innate immunity, which is systematically orchestrated in an orderly, balanced fashion in the healthy host. Such serine proteases are found in two well-recognized pathways of an innate immune network, coagulation and complement.
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