Results 281 to 290 of about 1,623,288 (319)
Some of the next articles are maybe not open access.
Studies on esterolytic activity of alternative complement component factor B
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1983Abstract Alternative complement component factor B was purified from human plasma and its esterolytic activity on various α-naphthylester derivatives was examined. Of these substrates, LeuAlaArg-naphthylester was the most susceptible. The K m value of factor B for this substrate was about 5·10 −4 M.
Michio Niinobe +3 more
openaire +3 more sources
Structure and activation of complement components C2 and Factor B
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984The activation of complement is initiated by two independent pathways. Each leads to the formation of a complex protease, C3 convertase, with equivalent specificity and function but different composition. The convertase derived from the classical pathway is composed of complement components C4 and C2 while that from the alternative pathway consists of ...
openaire +3 more sources
An assay for complement factor B in species at different levels of evolution
Developmental & Comparative Immunology, 1991The alternative complement pathway is regarded as the evolutionary ancestral complement system. It is therefore of interest to analyze and characterize factor B of the alternative complement pathway in animals at different levels of evolution. We describe a functional assay which is based on the interaction of factor B from various animal species with ...
Claus Koch, Lisbeth Bjerring Jensen
openaire +3 more sources
GENOMIC ANALYSIS OF THE F SUBTYPES OF HUMAN COMPLEMENT FACTOR B
International Journal of Immunogenetics, 1994SUMMARYFactor B of human complement is encoded within the Major Histocompatibility Complex (MHC) and is polymorphic, with up to 30 alleles defined by electrophoretic mobility. One of the most common alleles, BF*F, is subdivided into the FA and FB subtypes, which differ at the gene level by non‐synonymous base substitutions in the seventh codon. We have
I. Jahn +6 more
openaire +3 more sources
A New Complement Factor B Variant (BF S075) in Japanese
Human Heredity, 1990A new slow-moving variant of the complement factor B, named BF S075, was found in a Japanese patient with cerebral thrombosis and urticaria. The variant was inherited in a codominant manner. The protein concentration and functional hemolytic activity of the complement factor B in the patient's serum were within normal limits.
Takaaki Shinomiya +5 more
openaire +3 more sources
Duplication of the MHC-linked Xenopus complement factor B gene
Immunogenetics, 1995We have previously reported the molecular cloning of the mammalian major histocompatibility complex (MHC) class III gene, complement factor B (Bf) from Xenopus laevis, and linkage of the gene to the frog MHC. Here, we estimated the copy number of the Xenopus Bf gene by genomic Southern blotting analysis and demonstrated that Xenopus laevis has two ...
Makoto Sasaki +5 more
openaire +3 more sources
Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly
A Complement Factor B Mutation in a Large Kindred with Atypical Hemolytic Uremic Syndrome
Journal of Clinical Immunology, 2014M. Funato +10 more
semanticscholar +1 more source